CT-guided permanent brachytherapy for patients with medically inoperable early-stage non-small cell lung cancer (NSCLC)

The combined treatment of CT-guided percutaneous 125I seed implantation and chemotherapy for non-small-cell lung cancer

“…As shown in previous studies (Brach et al 1994;Heelan et al 1987;Martinez-Monge et al 2008;Zhang et al 2007), pneumothorax and hemoptysis were the main complications. In the present study, 5 patients had pneumothorax and 4 patients had hemoptysis.…”

CT-guided interstitial brachytherapy of inoperable non-small cell lung cancer

“…Follow-up radiologic evaluations were available for six patients, demonstrating complete or incomplete tumor shrinkage. Martínez-Monge et al [26] reported seven patients with early stage T1N0M0 NSCLC who had medical contraindications for surgical resection and were treated with CTguided percutaneous implantation of 103 Pd or 125 I seeds. After a median follow-up of 13 months, no patient has developed local or regional failure.…”

Primary Treatment Options for High-Risk/Medically Inoperable Early Stage NSCLC Patients

“…Martinez-Monge and colleagues 49 provided preliminary data with brachytherapy alone in 7 patients who were deemed to have medically inoperable early stage NSCLC. Brachytherapy was performed via CT-guided placement of Palladium-103 or Iodine-125 sources in tumors with an average volume of 11.5 cm 3 resulted in no local or regional failure with a median follow-up of 13-months.…”