2024
DOI: 10.1093/tropej/fmae017
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CTSG polymorphisms in Chinese children with type 1 diabetes mellitus

Jiaci Li,
Mingying Zhang,
Shuyue Zhang
et al.

Abstract: Cathepsin G (CTSG) plays an important role in the regulation of immune processes. Accumulated studies show that CTSG is involved in the onset and development of type 1 diabetes mellitus (T1DM). As the genetic background of T1DM varies widely among populations, we aimed to study the relationship between genetic polymorphisms in CTSG and T1DM susceptibility in Chinese populations. A total of 141 patients with T1DM and 200 healthy controls were enrolled in the study. Serum CTSG expression was detected using enzym… Show more

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