Cu AND Mn COMPLEXES OF NICOTINIC ACID AND IMIDAZOLE: A CURRENT REVIEW.

Khan, Shakeel Ahmad; Kanwal, Sadia; Iqbal, Ahsan; Ahmad, Waqar

doi:10.21474/ijar01/3959

IJAR

2017

DOI: 10.21474/ijar01/3959

|View full text |Cite

Cu AND Mn COMPLEXES OF NICOTINIC ACID AND IMIDAZOLE: A CURRENT REVIEW.

Shakeel Ahmad Khan¹,

Sadia Kanwal²,

Ahsan Iqbal³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2018

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 37 publications

(45 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

Synthesis, Spectroscopic Characterization and Biological Evaluation of Ni(II), Cu(II) and Zn(II) Complexes of Diphenyldithiocarbamate

Khan¹,

Ahmad²,

Munawar³

et al. 2018

pharmaceutical-sciences

View full text Add to dashboard Cite

Khan, et al.: Diphenyldithiocarbamate Complexes Synthesis and Biomedical Application Ni(II), Cu(II) and Zn(II) complexes of diphenyldithiocarbamate have been synthesized with the aim of developing antioxidants, potential antibacterial and antifungal agents. Synthesized metal complexes were characterized by magnetic susceptibility, elemental analysis; conductivity measurements, mass spectra, infrared, ultra violet/visible and nuclear magnetic resonance verified the chemical composition of products. Magnetic susceptibility and spectroscopic studies suggested the predicted geometry of the diphenyldithiocarbamate complexes as octahedral geometry of Ni(II) complex distortion square-planer geometry distorted towards tetrahedral for Cu(II) and Zn(II) complexes. Synthesized metal complexes exhibited remarkable antioxidant potential as compared to standard. Zn(II) complex of diphenyldithiocarbamate exhibited IC 50 of 31.45± 0.31 μM while the standard, butylated hydroxytoluene exhibited IC 50 of 44.67±0.45 μM antioxidant activity. Synthesized metal complexes showed very good antibacterial and antifungal potential against Rhodococcuss, Actinomyces viscosus, Bacillus subtilis, Escherichia coli and the fungi, Aspergillus niger, Aspergillus flavus, Candida and Acetomyceta. It's concluded that synthesized metal complexes showed better antioxidant, antibacterial and antifungal potential as compared to diphenyldithiocarbamate as well as the standard and might turn out to be a valuable treatment of numerous kinds of diseases.

show abstract

Synthesis, Spectroscopic Characterization and Biological Evaluation of Ni(II), Cu(II) and Zn(II) Complexes of Diphenyldithiocarbamate

Khan¹,

Ahmad²,

Munawar³

et al. 2018

pharmaceutical-sciences

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Cu AND Mn COMPLEXES OF NICOTINIC ACID AND IMIDAZOLE: A CURRENT REVIEW.

Cited by 1 publication

References 37 publications

Synthesis, Spectroscopic Characterization and Biological Evaluation of Ni(II), Cu(II) and Zn(II) Complexes of Diphenyldithiocarbamate

Synthesis, Spectroscopic Characterization and Biological Evaluation of Ni(II), Cu(II) and Zn(II) Complexes of Diphenyldithiocarbamate

Contact Info

Product

Resources

About