Cubic CeO<sub>2</sub>implanted reduced graphene oxide-based highly sensitive biosensor for non-invasive oral cancer biomarker detection

Pachauri, Namrata; Dave, Kashyap; Dinda, AK; Solanki, Pratima R.

doi:10.1039/c8tb00653a

Cited by 74 publications

(31 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…GO (blue line) revealed two peaks at 227 and 301 nm, which corresponds to the π‐π * and n‐π * electronic transitions, respectively. In the spectrum of CeO 2 (red line), a broad peak around 305 nm was observed, similar to previous literature . After decoration of GO with CeO 2, a red shift in the absorption spectrum was observed for CeO 2 @rGO nanocomposite (green line) revealing a broad peak at 320 nm.…”

Section: Resultssupporting

confidence: 88%

Tragacanth Hydrogel Integrated CeO₂@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation

et al. 2020

View full text Add to dashboard Cite

Sunlight‐driven photocatalytic degradation has attracted great attention to tackle the issue of water contaminating organic dyes. As a proof of concept, we propose that nanoceria (CeO2) decorated on the surface of reduced graphene oxide (rGO), could effectively degrade pollutant organic dyes namely methylene blue (MB) and congo red (CR), when exposed to sunlight. The formation of as‐synthesized nanocomposite (CeO2@rGO) was monitored using UV‐visible, Fourier transfer infrared (FTIR) and RAMAN spectroscopy, X‐ray diffraction (XRD), Photoluminescence (PL), and Field emission scanning electronic microscopy (FESEM). Time‐dependent dye degradation was observed for up to 5 h and followed Langmuir‐Hinshelwood first‐order kinetics. Notably, at equivalent concentrations (2 mg), CeO2@rGO exhibited enhanced degradation of MB (∼92 %) and CR (∼83 %) dyes when compared to bare CeO2. The photocatalytic efficiency of CeO2@rGO was further enhanced by integrating in a polymer hydrogel fabricated using tragacanth (TG), a natural gum. The hydrogel photocatalyst (CeO2@rGO‐TG) exhibited ∼91 % MB degradation, at half the amount of CeO2@rGO in free form. More importantly, CeO2@rGO‐TG could be easily separated from the dye solution and re‐employed for multiple cycles of degradation.

show abstract

Section: Resultssupporting

confidence: 88%

Tragacanth Hydrogel Integrated CeO₂@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation

et al. 2020

View full text Add to dashboard Cite

show abstract

“…The shape cannot be adequately identified due to the very small size and agglomeration among the particles . The very small sized nanoparticles with higher surface area lead to the agglomeration due to which well dispersed and individual particles could not be seen in the image . Though it is evident from the image that the nanoparticles were of very small (<10 nm) in size.…”

Section: Resultsmentioning

confidence: 97%

Ceria‐Nanoparticles‐Based Microfluidic Nanobiochip Electrochemical Sensor for the Detection of Ochratoxin‐A

et al. 2019

Self Cite

View full text Add to dashboard Cite

Ochratoxin-A (OTA) is a fungal mycotoxin that is present in most of the food stuff, and shows adverse effects on human beings. Therefore, the rapid and accurate detection of OTA is necessary. Here, ceria nanoparticles based microfluidic nanobiochip was fabricated for the electrochemical detection of OTA. Ceria nanoparticles were synthesized using a chemical coprecipitation method and characterized by various techniques. Raman spectroscopy confirmed the formation of fluorite cubic structure. Transmission electron microscopy (TEM) exhibited the formation of very small size (4-5 nm) with nearly spherical shape nanoparticles. Microfluidic nanobiochip was fabricated using 300 μm microfluidic channel using polydimethylsiloxane (PDMS). Simultaneously, indium tin oxide (ITO) coated Corning glass was used for the fabrication of immunoelectrodes platform using antibodies (anti-OTA) for the OTA detection. The detection range was achieved from 350 pg ml À 1 to 10 ng ml À 1 with sensitivity of 7.5 μA ng À 1 mL cm À 2 , without any interference effect using differential pulse voltammetry.

show abstract

“…In another work, cancer biomarker cytokeratin-fragment-21-1 was detected using a cerium oxide nanocubes-reduced graphene oxide-based nanocomposite. This electrochemical detection technique comprised of the thin films of the nanocomposite spin-coated onto electrodes with a specific antibody against the biomarker and utilized pulse voltammetry for signal detection [ 101 ]. A similar biosensor was developed that detects the cytokeratin-fragment-21-1 biomarker using a nanostructured yttrium oxide, nY 2 O 3 [ 102 ].…”

Section: Techniques Used For Diagnosis Of Oral Cancermentioning

confidence: 99%

Oral cancer diagnosis and perspectives in India

Borse

Konwar

Buragohain

2020

Sensors International

258

View full text Add to dashboard Cite

Globally, oral cancer is the sixth most common type of cancer with India contributing to almost one-third of the total burden and the second country having the highest number of oral cancer cases. Oral squamous cell carcinoma (OSCC) dominates all the oral cancer cases with potentially malignant disorders, which is also recognized as a detectable pre-clinical phase of oral cancer. Tobacco consumption including smokeless tobacco, betel-quid chewing, excessive alcohol consumption, unhygienic oral condition, and sustained viral infections that include the human papillomavirus are some of the risk aspects for the incidence of oral cancer. Lack of knowledge, variations in exposure to the environment, and behavioral risk factors indicate a wide variation in the global incidence and increases the mortality rate. This review describes various risk factors related to the occurrence of oral cancer, the statistics of the distribution of oral cancer in India by various virtues, and the socio-economic positions. The various conventional diagnostic techniques used routinely for detection of the oral cancer are discussed along with advanced techniques. This review also focusses on the novel techniques developed by Indian researchers that have huge potential for application in oral cancer diagnosis.

show abstract

Cubic CeO₂implanted reduced graphene oxide-based highly sensitive biosensor for non-invasive oral cancer biomarker detection

Abstract: Herein, we report a cerium oxide nanocubes (ncCeO2)–reduced graphene oxide (RGO)-based nanocomposite for the detection of oral cancer biomarker, cytokeratin fragment-21-1 (Cyfra-21-1), using the electrochemical technique.

Cited by 74 publications

References 56 publications

Tragacanth Hydrogel Integrated CeO₂@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation

Tragacanth Hydrogel Integrated CeO₂@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation

Ceria‐Nanoparticles‐Based Microfluidic Nanobiochip Electrochemical Sensor for the Detection of Ochratoxin‐A

Oral cancer diagnosis and perspectives in India

Contact Info

Product

Resources

About

Cubic CeO2implanted reduced graphene oxide-based highly sensitive biosensor for non-invasive oral cancer biomarker detection

Abstract: Herein, we report a cerium oxide nanocubes (ncCeO2)–reduced graphene oxide (RGO)-based nanocomposite for the detection of oral cancer biomarker, cytokeratin fragment-21-1 (Cyfra-21-1), using the electrochemical technique.

Cited by 74 publications

References 56 publications

Tragacanth Hydrogel Integrated CeO2@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation

Tragacanth Hydrogel Integrated CeO2@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation

Ceria‐Nanoparticles‐Based Microfluidic Nanobiochip Electrochemical Sensor for the Detection of Ochratoxin‐A

Oral cancer diagnosis and perspectives in India

Contact Info

Product

Resources

About

Cubic CeO₂implanted reduced graphene oxide-based highly sensitive biosensor for non-invasive oral cancer biomarker detection

Tragacanth Hydrogel Integrated CeO₂@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation

Tragacanth Hydrogel Integrated CeO₂@rGO Nanocomposite as Reusable Photocatalysts for Organic Dye Degradation