Cumulative live birth rate after up to three consecutive embryo transfer cycles in women with poor ovarian response

Kim, Se Jeong; Lee, Dayong; Kim, Seul Ki; Jee, Byung Chul; Kim, Seok Hyun

doi:10.5653/cerm.2019.03349

Cited by 2 publications

(3 citation statements)

References 12 publications

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“…After implementing POSEIDON criteria into clinical practice, many researchers have evaluated and compared ART outcomes among POSEIDON groups with or without normal ovarian responder and/or non-POSEIDON groups. The results differ between reported studies [17]- [23]. These studies include a variety of ethnicities ranging from Asian to Western countries.…”

Section: Discussioncontrasting

confidence: 74%

Comparison of ovarian induction outcome in Mongolian women classified by POSEIDON criteria

Dagvadorj,

Enkhmaa,

Erdenebileg

et al. 2024

Preprint

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Background Infertility has become a global issue, affecting 12.6–17.5% of women of reproductive age or 48.5 million couples. Infertility depends inversely on age, though, it is observed that young women are also now facing diminished ovarian reserve. Poor response to ovarian stimulation relates to the decreased ovarian reserve, and their remaining primordial, primary and secondary follicles have less sensitivity to Follicular stimulation hormone (FSH). The Patient-Oriented Strategy Encompassing Individualized Oocyte Number (POSEIDON) criteria have been proposed as a means to predict and plan the treatment of patients with poor ovarian responsiveness. Methods Here in, we report on implementation of the POSEIDON criteria for assessing ovarian response and compared assisted reproductive technology (ART) outcomes for women presenting with infertility at our clinic in Ulaanbaatar, Mongolia. Results The study included 158 women aged 23–45 years who were diagnosed with infertility. The participants’ mean age was 33.6 ± 5.3 years, their Body mass index (BMI) was 25.06 ± 3.86, and 88.0% (n = 139) of the patients were married. We evaluated the impact of the POSEIDON criteria on successful pregnancy by using logistic regression analysis. The probability of successful pregnancy is 2.2 times higher for POSEIDON group 1 and 2.3 times higher for group 2 compared to group 4. Conclusions The outcome of successful pregnancy can potentially be improved when assessing infertile Mongolian women and planning treatment by implementation of the use of the POSEIDON criteria.

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Section: Discussioncontrasting

confidence: 74%

Comparison of ovarian induction outcome in Mongolian women classified by POSEIDON criteria

Dagvadorj,

Enkhmaa,

Erdenebileg

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Numerous studies have evaluated and compared ART outcomes among POSEIDON groups with or without referring to the “non-POSEIDON” group, which is conventionally named the “normal ovarian responder” group, and there were varying results 9 – 15 . These studies were based on patients of different ethnicities, including Asian and Western countries; however, to the best of our knowledge, no study has evaluated Korean patients according to the POSEIDON classification.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, the POSEIDON group 2 showed a significantly higher pregnancy rate than its age-matched lower-ovarian-reserve counterpart group 4 ( p < 0.05, clinical pregnancy rates of 22.1% in group 2 and 4.8% in group 4). It has been well established that an AMH as low as 1.2 mg/mL is significantly correlated with poor ovarian response, especially in older patients 1 , 15 , 20 . Nevertheless, Tokura et al reported relative contraception probability among patients with POR over 40 years of age with AMH levels < 0.4 ng/mL 20 .…”

Section: Discussionmentioning

confidence: 99%

Comparison of ART outcome in patients with poor ovarian response according to POSEIDON criteria

Lee

Noh²,

Joo

2022

Sci Rep

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The aim of this study is to evaluate whether the patient-oriented strategies encompassing individualized oocyte number (POSEIDON) criteria can reflect the prognosis of controlled ovarian stimulation (COS) by comparing the results of assisted reproductive technologies (ART) between four POSEIDON and normal responder (NR) groups. In total, 225 patients were included in this retrospective observational study. The patients underwent various COS protocols and in vitro fertilization or intracytoplasmic sperm injection, followed by fresh or frozen embryo transfer. Based on their clinical and demographic data, patients were divided into four groups according to the POSEIDON classification, and their ART outcomes were evaluated. Statistical analyses were performed using R version 4.0.5, and a p-value of < 0.05 was considered significant. The NR group had the highest number of total oocytes retrieved and total embryos obtained, as well as the best ART outcome in terms of clinical pregnancy rate ([CPR], 47.6%). The POSEIDON groups 1 and 2 had better COS and ART outcomes than groups 3 and 4 (CPR, 22.6%, 22.1%, 16.7%, and 4.8% in groups 1–4, respectively); the patients in group 3 were younger than those in group 2 by definition, but their CPR was lower than that of patients in group 2. When comparing young and old women with low anti-Müllerian hormone (AMH) levels, the younger group (POSEIDON group 2) had better COS and ART outcomes than their older counterparts, especially POSEIDON group 4. A binary logistic regression adjusted for body mass index (BMI) comparing the ART outcomes of patients that did not get pregnant in the POSEIDON groups compared to the NR group showed odds ratios (ORs) (95% confidence interval) of 2.938 (1.496–5.768), 3.376 (1.848–6.167), 6.801 (2.740–16.881), and 20.497 (8.284–50.713) for groups 1, 2, 3, and 4, respectively. Ovarian reserve still seems to outweigh patients’ age when predicting the ART outcomes of low-responder infertile women, as suggested by the results of POSEIDON groups 2 and 3. However, when there are no differences in ovarian reserve, as in POSEIDON groups 2 and 4, younger women with low AMH have a higher probability of pregnancy than their AMH-matched older counterparts.

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Cumulative live birth rate after up to three consecutive embryo transfer cycles in women with poor ovarian response

Cited by 2 publications

References 12 publications

Comparison of ovarian induction outcome in Mongolian women classified by POSEIDON criteria

Comparison of ovarian induction outcome in Mongolian women classified by POSEIDON criteria

Comparison of ART outcome in patients with poor ovarian response according to POSEIDON criteria

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