Current advancements in polymer/polymer matrix composites for dental implants: A systematic review

Kadambi, Prasanna; Luniya, Pranay; Dhatrak, Pankaj

doi:10.1016/j.matpr.2020.12.396

Cited by 31 publications

(15 citation statements)

References 47 publications

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“…In recent years, biofilm-associated microbial infections on implantable medical devices have been a major concern and placed high burdens on healthcare systems. The implantable biomaterials include stainless steel, titanium (Ti), tantalum, zirconia, alumina, polyethylene, polyurethane, polytetrafluoroethylene (PTFE), and polyetherketoneketone (PEKK) [ 1 , 2 , 3 , 4 ]. Among these, the thermoplastic polyetheretherketone (PEEK) is a state-of-the-art material due to its superior chemical resistance, thermal stability, mechanical strength similar to cortical bone, and radiolucent property [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Facilitating GL13K Peptide Grafting on Polyetheretherketone via 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide: Surface Properties and Antibacterial Activity

Kumar

Tuong

et al. 2021

IJMS

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In the present work, the antimicrobial peptide (AMP) of GL13K was successfully coated onto a polyetheretherketone (PEEK) substrate to investigate its antibacterial activities against Staphylococcus aureus (S. aureus) bacteria. To improve the coating efficiency, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) was mixed with a GL13K solution and coated on the PEEK surface for comparison. Both energy-dispersive X-ray spectroscopy (EDX) and X-ray photoelectron spectroscopy (XPS) data confirmed 30% greater peptide coating on PEEK/GL13K-EDC than PEEK without EDC treatment. The GL13K graft levels are depicted in the micrograms per square centimeter range. The PEEK/GL13K-EDC sample showed a smoother and lower roughness (Rq of 0.530 µm) than the PEEK/GL13K (0.634 µm) and PEEK (0.697 µm) samples. The surface of the PEEK/GL13K-EDC was more hydrophilic (with a water contact angle of 24°) than the PEEK/GL13K (40°) and pure PEEK (89°) samples. The pure PEEK disc did not exhibit any inhibition zone against S. aureus. After peptide coating, the samples demonstrated significant zones of inhibition: 28 mm and 25 mm for the PEEK/GL13K-EDC and PEEK/GL13K samples, respectively. The bacteria-challenged PEEK sample showed numerous bacteria clusters, whereas PEEK/GL13K contained a little bacteria and PEEK/GL13K-EDC had no bacterial attachment. The results confirm that the GL13K peptide coating was able to induce antibacterial and biofilm-inhibitory effects. To the best of our knowledge, this is the first report of successful GL13K peptide grafting on a PEEK substrate via EDC coupling. The present work illustrates a facile and promising coating technique for a polymeric surface to provide bactericidal activity and biofilm resistance to medical implantable devices.

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Section: Introductionmentioning

confidence: 99%

Facilitating GL13K Peptide Grafting on Polyetheretherketone via 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide: Surface Properties and Antibacterial Activity

Kumar

Tuong

et al. 2021

IJMS

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“…Likewise, carbon-based nanodots, nanotubes, nanofibers, fullerenes, graphene derivatives, and nanocrystalline diamonds were reported to be beneficial a surface functionalization material to improve the surface property of the dental implant (Kang et al, 2021). Besides, nanosized polymers or polymer matrix composites, such as natural or biopolymers namely poly (lactic acid) and chitosan, synthetic polymers including polyetheretherketone (PEEK) and glycidyl methacrylate/triethylene glycol dimethacrylate (BisGMA/TEGDMA) are widely fabricated as nanoparticles or incorporated with nanoparticles to exhibit enhanced efficiency in dental implant applications (Kadambi et al, 2021).…”

Section: Carbon and Polymer Nanomaterialsmentioning

confidence: 99%

Plant-Derived Nanobiomaterials as a Potential Next Generation Dental Implant Surface Modifier

2021

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Dental implants resemble synthetic materials, mainly designed as teeth-mimics to replace the damaged or irregular teeth. Specifically, they are demarcated as a surgical fixture of artificial implant materials, which are placed into the jawbone, and are allowed to be fused with the bone, similar to natural teeth. Dental implants may be categorized into endosteal, subperiosteal, and zygomatic classes, based on the placement of the implant “in the bone” or on top of the jawbone, under the gum tissue. In general, titanium and its alloys have found everyday applications as common, successful dental implant materials. However, these materials may also undergo corrosion and wear, which can lead to degradation into their ionic states, deposition in the surrounding tissues, as well as inflammation. Consequently, nanomaterials are recently introduced as a potential alternative to replace the conventional titanium-based dental implants. However, nanomaterials synthesized via physical and chemical approaches are either costly, non/less biocompatible, or toxic to the bone cells. Hence, biosynthesized nanomaterials, or bionanomaterials, are proposed in recent studies as potential non-toxic dental implant candidates. Further, nanobiomaterials with plant origins, such as nanocelluloses, nanometals, nanopolymers, and nanocarbon materials, are identified to possess enhanced biocompatibility, bioavailability and no/less cytotoxicity with antimicrobial efficacy at low costs and ease of fabrication. In this minireview, we present an outline of recent nanobiomaterials that are extensively investigated for dental implant applications. Additionally, we discuss their action mechanisms, applicability, and significance as dental implants, shortcomings, and future perspectives.

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“…To overcome these issues, various coating procedures were developed, which showed more or less success. Deposition of a thin film of highly biocompatible material, such as some types of ceramics, biocompatible polymers, composites and matrixes that incorporate drug releasing agents, has been proposed [ 5 , 6 , 7 , 8 , 9 ], but issues regarding long-term stability, mainly due to the discrepancies between mechanical properties as well as poor adhesion and gradual changes of the interface, still persist. Furthermore, stainless steel contains traces of nickel, which is regarded as an allergenic and cytotoxic material [ 10 , 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Nanoporous Stainless Steel Materials for Body Implants—Review of Synthesizing Procedures

et al. 2022

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Despite the inadequate biocompatibility, medical-grade stainless steel materials have been used as body implants for decades. The desired biological response of surfaces to specific applications in the body is a highly challenging task, and usually not all the requirements of a biomaterial can be achieved. In recent years, nanostructured surfaces have shown intriguing results as cell selectivity can be achieved by specific surface nanofeatures. Nanoporous structures can be fabricated by anodic oxidation, which has been widely studied for titanium and its alloys, while no systematic studies are so far available for stainless steel (SS) materials. This paper reviews the current state of the art in the anodisation of SS; correlations between the parameters of anodic oxidation and the surface morphology are drawn. The results reported by various authors are scattered because of a variety of experimental configurations. A linear correlation between the pores’ diameter anodisation voltage was deduced, while no correlation with other processing parameters was found obvious. The analyses of available data indicated a lack of systematic experiments, which are recommended to understand the kinetics of pore formation and develop techniques for optimal biocompatibility of stainless steel.

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Current advancements in polymer/polymer matrix composites for dental implants: A systematic review

Cited by 31 publications

References 47 publications

Facilitating GL13K Peptide Grafting on Polyetheretherketone via 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide: Surface Properties and Antibacterial Activity

Facilitating GL13K Peptide Grafting on Polyetheretherketone via 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide: Surface Properties and Antibacterial Activity

Plant-Derived Nanobiomaterials as a Potential Next Generation Dental Implant Surface Modifier

Nanoporous Stainless Steel Materials for Body Implants—Review of Synthesizing Procedures

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