Current Asthma Guidelines May Not Identify Young Children Who Have Experienced Significant Morbidity

Galant, Stanley P.; Morphew, Tricia; Amaro, Silvia; Liao, Otto

doi:10.1542/peds.2005-1076

Cited by 34 publications

(24 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…There is no gold standard for diagnosing asthma nor for rating the severity of the condition. However, a recent study concludes that the 2002 National Asthma Education and Prevention Program (NAEPP) guidelines, based on symptom-frequency as used in this study, seem to offer a valid basis for classifying asthma severity in those greater than 5 years of age (43). However, this method may underclassify younger children (43).…”

Section: Severity Of Asthma (Dependent Variable)mentioning

confidence: 81%

Severity of Childhood Asthma and Human Leukocyte Antigens Type

Juhn¹,

Kita²,

Bagniewski³

et al. 2007

Journal of Asthma

View full text Add to dashboard Cite

We sought to learn if Class II HLA genes are associated with the severity of asthma in children. We examined a previously recruited cohort of 340 healthy children who had Class II HLA allele data available. We conducted a comprehensive review of their medical records to determine asthma status and, when present, its severity. We found that Class II HLA alleles, which were previously reported to have an association with asthma incidence, appear to have an association as well with asthma severity. These data support our hypothesis that both the incidence and severity of asthma are heritable and that HLA may play an important role in both development and severity of asthma. Because of limited statistical power, our study findings are subject to further investigation.

show abstract

Section: Severity Of Asthma (Dependent Variable)mentioning

confidence: 81%

Severity of Childhood Asthma and Human Leukocyte Antigens Type

Juhn¹,

Kita²,

Bagniewski³

et al. 2007

Journal of Asthma

View full text Add to dashboard Cite

show abstract

“…A escolha do desenho, controle histórico, mesmo com limitações, impôs-se frente às dificuldades de desenvolver um estudo de avaliação em uma cidade com a complexidade de Belo Horizonte, além de ser apontado por Gordis 14 hospitalização e de atendimentos de urgência como parâ-metros para avaliar tratamentos preventivos na asma 6,[16][17][18][19][20][21][22][23][24] . Por outro lado, essas variáveis são quantificáveis e também fatos marcantes na vida do paciente, reduzindo o viés de memória 25,26 .…”

Section: Discussionunclassified

Impact of an asthma management program on hospitalizations and emergency department visits

et al. 2011

View full text Add to dashboard Cite

Objectives: To assess the frequency of hospitalizations and emergency department visits of children and adolescents before and after the enrolment in an asthma program.Methods: Medical records of 608 asthmatics younger than 15 years were assessed retrospectively. The frequency of hospitalizations and emergency department visits caused by exacerbations were evaluated before and after enrolment in an asthma program. Patients were treated with medications and a wide prophylactic management program based on the Global Initiative for Asthma (GINA). The before asthma program (BAP) period included 12 months before enrollment, whereas the after asthma program (AAP) period ranged from 12 to 56 months after enrollment. Results:In the BAP period, there were 895 hospitalizations and 5,375 emergency department visits, whereas in the AAP period, there were 180 and 713, respectively. This decrease was significant in all statistical analyses (p = 0.000). Conclusions:Compliance with the GINA recommendations led to a significant decrease in the frequency of hospitalizations and emergency department visits in children and adolescents with asthma.J Pediatr (Rio J). 2011;87(5):412-8: Asthma, hospitalisation, emergency medical services, continuing education, primary health care. ResumoObjetivo: Analisar as frequências de hospitalização e de atendimentos em serviços de urgência ocorridas em crianças e adolescentes antes e após o ingresso em programa de asma no Brasil. Métodos:Prontuários de 608 pacientes menores de 15 anos e com asma foram avaliados retrospectivamente. As frequências de hospitalização por asma e de atendimentos em serviços de urgência para episó-dios agudos de broncoespasmo foram avaliadas nos períodos anterior e posterior à admissão no programa que disponibiliza medicamentos, preconiza abordagem integral do paciente e manejo profilático de acordo com a Global Initiative for Asthma (GINA). O período de observação antes do programa (AP) teve a duração de 12 meses enquanto o depois do programa (DP) variou de 12 a 36 meses. Resultados:No período AP, ocorreram 895 hospitalizações e 5.375 atendimentos em serviços de urgência, e no período DP, ocorreram 180 hospitalizações e 713 atendimentos na urgência. O teste t de Student para amostras pareadas e o modelo de regressão para observações dependentes identificaram efeito significativo do programa em relação às variáveis estudadas (p = 0,000). Conclusões:A adoção das recomendações do GINA levou à redução significativa nas frequências de hospitalização e atendimentos na urgência em crianças e adolescentes com asma. J Pediatr (Rio J). 2011;87(5):412-8:Asma, hospitalização, atendimento de emergência, educação continuada, atenção básica à saúde. Impact of an asthma management program on hospitalizations and emergency department visitsImpacto de um programa de manejo da asma sobre as hospitalizações e os atendimentos de urgência IntroduçãoA asma, reconhecido problema de saúde pública, vem apresentando aumento na prevalência nas últimas décadas em algumas partes do mundo, ...

show abstract

“…Children who are at risk for exacerbations from asthma may not experience greater asthma symptoms before the onset of the severe exacerbation. 9 To our knowledge, no studies have examined both the predictors of asthma symptoms and the predictors of severe exacerbations using longitudinal data in children. Predictors of asthma symptoms in adults include use of oral corticosteroids, comorbid illnesses, higher BMI, and low income.…”

Section: Data Collectionmentioning

confidence: 99%