Current Concepts in the Diagnosis of Primary Open Angle Glaucoma

Omoti, A E; Okeigbemen, Valentina W; Waziri-Erameh, J M

doi:10.4314/wajm.v28i3.48480

Cited by 4 publications

(3 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although an elevated IOP is a significant risk factor for the development of glaucoma, it is important to note that sight-threatening effects of glaucoma are not necessarily coming from increased IOP but from retinal and optic nerve neurodegeneration. There are examples of patients that have normal pressure glaucoma (NPG), as well as patients with no retinal damage that have chronically high IOP [23][24][25] . Even in a DBA/2J mouse, a model for secondary angle-closure glaucoma, it has been shown that hypertension is not the only causative factor in glaucomatous optic neuropathy 26 .…”

Section: Discussionmentioning

confidence: 99%

In Vivo Gene Expression Profiling of Retina Postintravitreal Injections of Dexamethasone and Triamcinolone at Clinically Relevant Time Points for Patient Care

Smit-McBride

Modjtahedi

Cessna

et al. 2011

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

In Vivo Gene Expression Profiling of Retina Postintravitreal Injections of Dexamethasone and Triamcinolone at Clinically Relevant Time Points for Patient Care

Smit-McBride

Modjtahedi

Cessna

et al. 2011

Invest. Ophthalmol. Vis. Sci.

View full text Add to dashboard Cite

show abstract

“…Estrogens play an important role in angiogenesis, ensuring vasodilation and preparing for uterine contraction, in addition to promoting catabolic metabolism and enlargement of the mammary glands. Since the gestational period is related to physiological, pathological changes or modifications of certain conditions, we have to take into account the tissue changes that may occur (OMOTI, et al, 2008).…”

Section: Resultsmentioning

confidence: 99%

Refractive errors during pregnancy: A bibliographic review

Cavalli¹,

Bettes²,

Friedrich³

et al. 2023

Development and Its Applications in Scientific Knowledge

View full text Add to dashboard Cite

Introduction: During pregnancy, many physiological changes occur in women secondary to the metabolic demands of the fetus, placenta, and uterus and the increasing levels of sex hormones. The hormonal peak is characterized by the increase in estrogen, progesterone, and androgen which have receptors in various tissues, with the ability to modify them. The purpose of the research is to analyze the emergence/progression of refractive errors during pregnancy, describe the pathophysiology, identify if there is an improvement in the postpartum period, if there is a need for treatment, and verify the relationship between the mode of delivery and the RE. Material and methods: A bibliographic review was carried out with research restrictions from 2000 to 2022, being selected thirty-one studies. It also had a theoretical basis in books and reports. Results and discussions: Since the gestational period is related to physiological, pathological changes or changes in certain conditions, we have to take into account that the ocular tissues can change. The presence of sex hormone receptors in eye tissues been observed, which are affected during pregnancy, causing eye disorders to be exacerbated or ameliorated. Conclusion: Most authors conclude that RE can occur during pregnancy, however, many have inconclusive results. RE are physiological changes during this period, not requiring treatment, as they tend to regress after delivery. Changes in the RE and the mode of delivery should not be taken into account. More research is needed on the subject, as many articles contradict each other, despite the changes in the cornea being confirmed.

show abstract

“…Health insurance needs to be restructured to accommodate all citizens irrespective of their job status. A simple and systematic approach in examination will improve accurate diagnosis of glaucoma [61] and provide basis for appropriate management. Preventing glaucoma blindness in low income economy is a hard task, but it is never late to start.…”

Section: Treatment Of Poagmentioning

confidence: 99%

Epidemiological Properties of Primary Open Angle Glaucoma in Nigeria

Abdu

2013

Journal of Ophthalmology

View full text Add to dashboard Cite

Background. Primary open angle glaucoma (POAG) is progressive chronic optic neuropathy in adults in which intraocular pressure (IOP) and other currently unknown factors contribute to damage. POAG is the second commonest cause of avoidable blindness in Nigeria. Pattern of Presentation. POAG is characterized by late presentation. Absence of pain which is a driving force for seeking medical help, inadequacy of trained eye care personnel, paucity of facilities, misdistribution of resources, lack of awareness, poor education, and poverty may all contribute to this. Medical and surgical treatment options available are challenging and tasking. Screening for Glaucoma. Screening is the presumptive identification of unrecognized disease (POAG) by applying test(s) which can be applied rapidly. Such test(s) should be of high reliability, validity, yield, acceptable, and cost effective. The test should ideally be sensitive, specific, and efficient. It is difficult to select a suitable test that meets these criteria. Intraocular pressure (IOP) appears to be the easiest option. But, high IOP is not diagnostic nor does normal value exclude the disease. Health education is a possible strategy in early case detection and management. Treatment of POAG. Glaucoma treatment can either be medical or surgical (this includes laser). Considering unavailability, potency, cost, and long-term effects of medication, surgery (trabeculectomy) could be a better option. Laser trabeculoplasty is available in a few centers. Viscocanalostomy is not routinely performed. Patient education is vital to success as management is for life. Conclusion. POAG remains a cause of avoidable blindness in Nigeria. There is need for long-term strategy to identify patients early and institute prompt management. Improvement in training of eye care personnel and provision of up to date equipment is essential in achieving this goal.

show abstract

Current Concepts in the Diagnosis of Primary Open Angle Glaucoma

Abstract: BACKGROUND: Primary open angle glaucoma is characterized by quantifiable parameters including the intraocular pressure, the aqueous outflow facility, and geometric measurements of the optic disc and visual defects. Despite this, diagnosis remains controversial.

Cited by 4 publications

References 27 publications

In Vivo Gene Expression Profiling of Retina Postintravitreal Injections of Dexamethasone and Triamcinolone at Clinically Relevant Time Points for Patient Care

In Vivo Gene Expression Profiling of Retina Postintravitreal Injections of Dexamethasone and Triamcinolone at Clinically Relevant Time Points for Patient Care

Refractive errors during pregnancy: A bibliographic review

Epidemiological Properties of Primary Open Angle Glaucoma in Nigeria

Contact Info

Product

Resources

About