Current Diagnostic Algorithm of HIV and Emerging Prevention Methods

Aslan, Ferhat Gürkan; Altındiş, Mustafa

doi:10.5222/tmcd.2017.047

Cited by 3 publications

(6 citation statements)

References 30 publications

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“…The answers of the students to some questions were detailed examined. *The correct answers are marked with an asterisk (questions [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18]. Instead of determining the correct answer regarding ethical issues, we marked the answers of the majority with an asterisk.…”

Section: Resultsmentioning

confidence: 99%

“…There isn't radical treatment of AIDS today. However, quality of life and duration of the patient can be increased with various antiviral drugs 3,12 .…”

Section: Discussionmentioning

confidence: 99%

“…HIV (Human immunodeficiency virus) in the Retroviridae family is a lentivirus with double polarity RNA 1,2 . AIDS (Acquired Immune Deficiency Syndrome) is a human immune system disease caused by HIV 3 . AIDS disrupts the function of immune system cells, which is a duty of preventing infections, this results in immunosuppression leading to opportunistic infections and associated complications 4,5 .…”

Section: Introductionmentioning

confidence: 99%

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What Do Medical Students Think About HIV/AIDS? Student thoughts on HIV / AIDS

Can

2021

Dicle Tıp Dergisi

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Objective: With this study, we wanted to reduce the transmission of HIV/AIDS and to improve the attitudes and behaviors of physician candidates towards HIV/AIDS patients. For this reason, we first measured the knowledge levels of the students. Raising awareness of doctor candidates is a strategic move to protect against HIV / AIDS and to make these patients benefit from health services without any problem.Methods: Using a questionnaire, we measured HIV/AIDS knowledge levels of students (960) who were continuing their education in the medical school of Atatürk University. The questionnaire consisted of five parts: demographic characteristics, general information, ways of transmission, ways of protection, attitudes, and behaviors. Ethics committee permission was obtained for the study and the survey data were analyzed in SPSS 20 package program. Results:We noticed that physician candidates, especially ethical issues, were confused in some questions. The results were not enough for medical school. 960 volunteers participated in the study, of which 532 (55.4%) were women and 428 (44.6%) were men. The students knew that an HIV carrier and a patient diagnosed with AIDS are different from each other (78.2%). They said that HIV is a virus that weakens the immune system (86%) and AIDS has no radical treatment (97.4%). However, students' answers about pregnant women and nursing mothers were discrepancy. Conclusion:We saw that young people need education on HIV/AIDS. For this reason, a training seminar was given by the academicians at Atatürk University on World AIDS Day. The students who participated in our study and education stated that they were not afraid of the patients with AIDS and learned the subject. We expect that this training will improve the approach of doctor candidates to the patient and that the provision of training in all faculties will reduce the increase in HIV / AIDS.

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Section: Resultsmentioning

confidence: 99%

“…There isn't radical treatment of AIDS today. However, quality of life and duration of the patient can be increased with various antiviral drugs 3,12 .…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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What Do Medical Students Think About HIV/AIDS? Student thoughts on HIV / AIDS

Can

2021

Dicle Tıp Dergisi

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“…As the results of macro-ELISA method were examined according to the confirmation tests, the lowest Anti-HIV value as true reactive was determined as 9.36 s/co, and the highest Anti-HIV value as false reactive was determined as 173.92 s/co. (7). Western Blot has been commonly performed as confirmation test, but it has been replaced by HIV-1/2 antibody differentiating rapid confirmation tests in the world and in our country due to its low sensitivity rate, excess of cross-reactions and demanding test properties.…”

Section: E a R L Ymentioning

confidence: 99%

“…In this context, in order to control the HIV epidemic, implementing the 90-90-90 targets (Diagnosing 90% of HIV-infected people, initiating antiretroviral therapy in 90% of people diagnosed, providing viral suppression among 90% of patients who receive antiretroviral therapy) holds great importance for the UNAIDS organization (6). For disease control, early, accurate and rapid diagnosis and initiation of treatment as soon as possible is the key point in terms of reducing the individual's mortality and morbidity as well as preventing transmission among the community (7). The aim of this study was to evaluate the anti-HIV seropositivity and the results of confirmation tests in patients admitted to our hospital between 2014 and 2019 and so to contribute to Turkey's epidemiological data.…”

Section: Introductionmentioning

confidence: 99%

HIV Seropositivity in Patients Admitted to Our Hospital: Six Year Evaluation

Bahçeci

Yıldız

2021

Düzce Tıp Fakültesi Dergisi

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Aim: Detecting human immunodeficiency virus (HIV)-infected individuals is very important in terms of quality of patients' lives. However, it should be kept in mind that there may be false positives and tests must be confirmed. In this study, it was aimed to determine HIV seropositivity in our hospital for a period of six years and to contribute to the epidemiological data of the country. Material and Methods: The samples that came to serology laboratory between January 2014 and December 2019 were analyzed retrospectively. Anti-HIV antibodies were screened in a total of 180,413 samples by the macro-ELISA method (Architect i2000sr, Abbott, USA). Patient samples were sent to the National HIV/AIDS Confirmation and Viral Hepatitis Reference Laboratory for verification of reagents results. Results: Anti-HIV results of 178 (0.1%) of 180,413 patients whose blood serum samples were studied with the macro-ELISA method were evaluated as reactive. Confirmation test of 102 patients were negative while 76 were positive. Patients with positive confirmation result account for 0.04% of all patients. While 67 (88.2%) of the patients with positive confirmation were male and 9 (11.8%) were female. The ages of 26-35 and 36-45 years were equal with the highest number of new cases detected (n=20, 26.3%). Conclusion: As a result of our retrospective evaluation, HIV seropositivity, gender and age distributions in our hospital were found to be compatible with the data of our country and other studies conducted in our country. The high false positivity rate of screening tests, again indicates the importance of confirmation tests.

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Positive Anti-HIV ELISA Results in Pregnancy: Is It Reliable?

Güler

Arıkan

Abobakr

et al. 2022

Infectious Diseases in Obstetrics and Gynecology

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Background: Human immunodeficiency virus (HIV) can be transmitted from mothers to their babies during pregnancy, delivery through vaginal fluids or breastfeeding. As false positivity anti-HIV results due to pregnancy could be detected and no relevant study have been reported in Northern Cyprus so far, we aimed to estimate the false anti-HIV positivity rate in pregnant women. Methods: A total of 11.977 women admitted to Near East University Hospital between 2015 and 2018 were involved. The fourth generation anti-HIV-1/2 ELISA test was carried out by chemiluminescence enzyme immunoassay. Positive results were confirmed by real-time polymerase chain reaction (rt-PCR). SPSS (Statistical Package for the Social Sciences) Demo Ver 22 program was used for statistical analysis and significance (p<0.05) was measured by Person Chi-Square and Fisher's Exact tests. Results: Anti-HIV-1/2 ELISA test was positive in 7 (0.3%) of pregnant and 11 (0.1%) of non-pregnant women. HIV RNA was not detected in any pregnant however, was detected in 2 (0.02%) of non pregnant. S/Co titer of pregnant and non pregnant who have positive anti-HIV-test without viral load was x̄=2.68±1.64 (1.34-5.20) and x̄=8.63±7.68 (1.56-20.98) respectively. False positivity was significantly higher in pregnants compared to non-pregnants (p=0.033). Conclusion: False positivity can be encountered during pregnancy therefore, positive anti-HIV-1/2 ELISA results should be confirmed with molecular techniques before initiating antiretroviral treatment.

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Current Diagnostic Algorithm of HIV and Emerging Prevention Methods

Cited by 3 publications

References 30 publications

What Do Medical Students Think About HIV/AIDS? Student thoughts on HIV / AIDS

What Do Medical Students Think About HIV/AIDS? Student thoughts on HIV / AIDS

HIV Seropositivity in Patients Admitted to Our Hospital: Six Year Evaluation

Positive Anti-HIV ELISA Results in Pregnancy: Is It Reliable?

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