Current diagnostic imaging of pulmonary and cerebral paragonimiasis, with pathological correlation

Im, Jung-Gi; Chang, Kee-Hyun; Reeder, Maurice M.

doi:10.1016/s0037-198x(97)80024-7

Cited by 48 publications

(19 citation statements)

References 20 publications

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“…The genus Paragonimus was established by Diesing in 1850, while working in Brazil. The first human infection was documented in 1879, in Taiwan (129).…”

Section: Historymentioning

confidence: 99%

Update on Eosinophilic Meningoencephalitis and Its Clinical Relevance

2009

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SUMMARY Eosinophilic meningoencephalitis is caused by a variety of helminthic infections. These worm-specific infections are named after the causative worm genera, the most common being angiostrongyliasis, gnathostomiasis, toxocariasis, cysticercosis, schistosomiasis, baylisascariasis, and paragonimiasis. Worm parasites enter an organism through ingestion of contaminated water or an intermediate host and can eventually affect the central nervous system (CNS). These infections are potentially serious events leading to sequelae or death, and diagnosis depends on currently limited molecular methods. Identification of parasites in fluids and tissues is rarely possible, while images and clinical examinations do not lead to a definitive diagnosis. Treatment usually requires the concomitant administration of corticoids and anthelminthic drugs, yet new compounds and their extensive and detailed clinical evaluation are much needed. Eosinophilia in fluids may be detected in other infectious and noninfectious conditions, such as neoplastic disease, drug use, and prosthesis reactions. Thus, distinctive identification of eosinophils in fluids is a necessary component in the etiologic diagnosis of CNS infections.

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“…The genus Paragonimus was established by Diesing in 1850, while working in Brazil. The first human infection was documented in 1879, in Taiwan (129).…”

Section: Historymentioning

confidence: 99%

Update on Eosinophilic Meningoencephalitis and Its Clinical Relevance

2009

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“…Eggs of North American P. kellicotti seem to elicit a particularly strong infl ammatory response and pleural symptoms and effusion are usual [ 42 ]. Since cysts containing adult worms tend to be peripheral in the lungs, often close to pleural surfaces [ 190 ], it is not surprising that some cysts discharge eggs into pleural spaces [ 42 ].…”

Section: Pleural Manifestationsmentioning

confidence: 99%

“…Symptoms may be more pronounced in heavy infections. A proportion of individuals, even those with heavy pulmonary infections, remain symptom-free [ 190 ].…”

Section: Pulmonary Manifestationsmentioning

confidence: 99%

“…Distinct cystic lesions and nodules less than 3-4 cm in diameter and bronchiectasis tend to be seen in established infections [ 19 , 190 ]. Cysts may appear as ring shadows, within which worms may be detected in some cases [ 190 ]. Pleural thickening may be present adjacent to worm nodules [ 263 ].…”

Section: Radiology/medical Imagingmentioning

confidence: 99%

“…In early "active" infection, characteristic ring-like granulomatous lesions are commonly seen using CT scans. These may be solitary or resemble clusters of grapes, each usually 1-3 cm in diameter and each surrounded by edematous areas [ 190 ]. Later these become calcifi ed, resembling "soap-bubbles" or egg-shells with surrounding parenchymal damage [ 190 ].…”

Section: Radiology/medical Imagingmentioning

confidence: 99%

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Paragonimiasis

Blair

2014

Advances in Experimental Medicine and Biology

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MRI features of pediatric cerebral paragonimiasis in the active stage

Zhang¹,

Yi²,

Sun³

et al. 2006

Magnetic Resonance Imaging

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We retrospectively reviewed the MR images of the brains of six children (age = 5–13 years) who had cerebral paragonimiasis in the early active stage. Diagnosis was based on a positive antibody test enzyme‐linked immunosorbent assay (ELISA) for paragonimiasis in serum. The most common finding (in five patients) was irregular hemorrhage of various degrees. Moreover, in three cases some multiple irregular lesions with surrounding edema appeared to be conglomerated and aggregated. The rare appearance (in one patient) was a “tunnel sign,” which showed the migrating track of the adult worm. In one patient with abscess and minimal hemorrhage, diffusion‐weighted imaging (DWI) showed a heterogeneous high signal of lesions. Other findings included slight (one patient) or marked (one patient) irregular contrast enhancement, and large edematous areas surrounding small centers of hemorrhage (two patients). MR findings of conglomerated lesions with hemorrhage or tunnel sign may help to establish the diagnosis of active‐stage cerebral paragonimiasis. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.

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Current diagnostic imaging of pulmonary and cerebral paragonimiasis, with pathological correlation

Cited by 48 publications

References 20 publications

Update on Eosinophilic Meningoencephalitis and Its Clinical Relevance

Update on Eosinophilic Meningoencephalitis and Its Clinical Relevance

Paragonimiasis

MRI features of pediatric cerebral paragonimiasis in the active stage

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