Current Incidence of Different Morphological Types of Malignant Metastases to the Spine Based on Magnetic Resonance Imaging

Guzik, Grzegorz

doi:10.5604/15093492.1238001

Cited by 4 publications

(18 citation statements)

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“…The skeletal system is the third most frequent location of neoplastic metastases after the lungs and liver [ 5 ]. Although bone metastases are an expression of a significant advancement of the neoplastic process, it is sometimes the first and only symptom of a neoplastic disease that manifests itself clinically or radiologically [ 5 , 6 ]. If the metastasis to the bones is a secondary symptom of neoplastic disease, the period between the onset and treatment of the primary lesion and the disclosure of a metastatic focus in the spine can be of different lengths.…”

Section: Introductionmentioning

confidence: 99%

“…The spine is the most frequent site of bone metastasis [ 2 ]. In postmortem examinations of neoplastic disease, metastatic foci in the spine are found in 30 to 70% of cases [ 6 ]. The primary tumor sites include the breasts, prostate, kidneys, lungs, multiple myeloma, thyroid gland, larynx, ovaries, large intestine, or liver.…”

Section: Introductionmentioning

confidence: 99%

“…The frequency of metastases from the locations mentioned above is adequate for the number of people with the corresponding primary tumor in a given population. Their peak incidence occurs in the sixth and seventh decades of life [ 4 , 6 ]. Metastatic tumors of the spine are located in different spine sections ( Figure 1 ).…”

Section: Introductionmentioning

confidence: 99%

“…Metastatic tumors of the spine are located in different spine sections ( Figure 1 ). A large group (18%) are multi-site metastases involving more than one section of the spine [ 6 ]. Some metastatic neoplasms show a clear predilection to specific parts of the spine, e.g., lung and breast cancers often metastasize to the thoracic section, while cancers of the prostate and colon often metastasize to the lumbar compartment [ 5 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

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Holistic Approach to the Diagnosis and Treatment of Patients with Tumor Metastases to the Spine

Nowak

Szwacka

Pater

et al. 2022

Cancers

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The treatment of neoplastic spine metastases requires multi-faceted assessment and an interdisciplinary approach to patients. The metastases do not show specific symptoms but are often the first confirmation of the presence of a primary tumor in a patient. The diagnostic process includes imaging and invasive procedures, e.g., biopsy. It is essential to qualify the patient for an appropriate treatment using dedicated scales. Decompression of the spinal cord is a critical issue to save or restore neurological function in a patient with spine metastases. Surgical treatment ought to meet three criteria: release spinal cord and nerve roots, restore the spine’s anatomical relations, and ensure the internal stabilization of the spine. A good result from surgical treatment enables the continuation of radiotherapy, chemotherapy, hormone therapy, and targeted molecular therapy. Stereotactic radiosurgery and stereotactic body radiotherapy are more effective ways of treating spine metastases than conventional external beam radiotherapy. They allow higher doses of radiation, concentrated precisely at the tumor site. Our review summarizes the established and emerging concepts in the treatment of spine metastases. A holistic approach to the patient enables the selection of the appropriate therapy.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Holistic Approach to the Diagnosis and Treatment of Patients with Tumor Metastases to the Spine

Nowak

Szwacka

Pater

et al. 2022

Cancers

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“…Spinal osseous tumors have complex lesion types, which can be divided into metastatic tumor and primary tumor, in which primary spinal osseous tumor is a rare tumor disease taking up approximately 7% in systemic tumors, and its rate of deterioration is relatively high with the occurrence of disease (1,2). The highest proportion of metastatic tumor is >50%, half of which are benign tumors and the remaining half are malignant tumors.…”

Section: Introductionmentioning

confidence: 99%

Imaging features of primary spinal osseous tumors and their value in clinical diagnosis

Yang

Zhang

et al. 2018

Oncol Lett

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This study explored the method of imaging diagnosis of primary spinal osseous tumors and the application value of imaging in clinical diagnosis. Sixty-nine patients with primary spinal osseous tumors who received treatment in Nankai Hospital from July 2016 to June 2017 were selected. All of them received X-ray, computed tomography (CT) and magnetic resonance imaging (MRI) examinations to analyze the imaging features of the three examination methods. Sensitivity (Sen), specificity (Spe), positive predictive value (PV+), negative predictive value (PV−) and accuracy (Acc) were compared. The consistency of the three examination methods in diagnosing primary spinal osseous tumors was analyzed. Sen, Acc and PV− of the three examination methods in diagnosing spinal osseous tumors had obvious differences. MRI showed the highest Sen (P<0.05). MRI had relatively high consistency with CT scan in diagnosing primary spinal osseous tumors, and κ-value was 0.72. CT scan and X-ray had obvious difference in diagnosing primary spinal osseous tumors (P<0.05). The consistency between CT scan and X-ray in diagnosing primary spinal osseous tumors was relatively low, and κ-value was 0.47. MRI and X-ray had obvious difference in diagnosing primary spinal osseous tumors (P<0.05). The consistency between MRI and X-ray in diagnosing primary spinal osseous tumors was relatively low, and κ-value was 0.41. X-ray examination is easy to operate with high resolution. CT scan has obvious advantages in displaying lesions with complex structure, many of which locate in overlapping sites. MRI has more advantages and higher accuracy in judging the scope of the tumor. CT and MRI examinations have obviously higher efficacy than X-ray in diagnosing primary spinal osseous tumors. They are conducive in improving the accuracy of diagnosing primary spinal osseous tumors.

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Evaluate the characteristics and clinical significance of “toxic twin-leaf” sign in spinal epidural metastases before percutaneous vertebroplasty

Sun

Tian

et al. 2020

Journal of Interventional Medicine

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Current Incidence of Different Morphological Types of Malignant Metastases to the Spine Based on Magnetic Resonance Imaging

Abstract: The Tomita system allows for easy and clear classification of the morphology of malignant metastases. 66% of patients treated at our department had multisite T6 or T7 metastases.

Cited by 4 publications

References 0 publications

Holistic Approach to the Diagnosis and Treatment of Patients with Tumor Metastases to the Spine

Holistic Approach to the Diagnosis and Treatment of Patients with Tumor Metastases to the Spine

Imaging features of primary spinal osseous tumors and their value in clinical diagnosis

Evaluate the characteristics and clinical significance of “toxic twin-leaf” sign in spinal epidural metastases before percutaneous vertebroplasty

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