Current nanotechnology advances in diagnostic biosensors

Barbosa, Ana I.; Rebelo, Rita; Reis, Rui L.; Bhattacharya, Mrinal; Correlo, Vítor M.

doi:10.1002/mds3.10156

Cited by 30 publications

(7 citation statements)

References 284 publications

(435 reference statements)

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“…Nanoparticles have a great volume-to-surface relationship compared to higher elements, so it is important to assess and monitor their surface characteristics accurately ( 28 ). A ZP analyzer can determine the surface charge, also known as zeta potential (ZP).…”

Section: Characterization Of Lbnpsmentioning

confidence: 99%

Lipid-based nanoparticles as drug delivery carriers for cancer therapy

Waheed,

Ali,

Tabassum

et al. 2024

Front. Oncol.

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Cancer is a severe disease that results in death in all countries of the world. A nano-based drug delivery approach is the best alternative, directly targeting cancer tumor cells with improved drug cellular uptake. Different types of nanoparticle-based drug carriers are advanced for the treatment of cancer, and to increase the therapeutic effectiveness and safety of cancer therapy, many substances have been looked into as drug carriers. Lipid-based nanoparticles (LBNPs) have significantly attracted interest recently. These natural biomolecules that alternate to other polymers are frequently recycled in medicine due to their amphipathic properties. Lipid nanoparticles typically provide a variety of benefits, including biocompatibility and biodegradability. This review covers different classes of LBNPs, including their characterization and different synthesis technologies. This review discusses the most significant advancements in lipid nanoparticle technology and their use in medicine administration. Moreover, the review also emphasized the applications of lipid nanoparticles that are used in different cancer treatment types.

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Section: Characterization Of Lbnpsmentioning

confidence: 99%

Lipid-based nanoparticles as drug delivery carriers for cancer therapy

Waheed,

Ali,

Tabassum

et al. 2024

Front. Oncol.

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“…This selective detection is helpful for applications like gas sensing, where different gases have distinct infrared absorption spectra. 43,44 Integrating three-dimensional (3D) printing and additive manufacturing techniques could revolutionize the fabrication of NEMS/MEMS-based sensors. This could allow for more complex and customized sensor designs, while reducing production costs.…”

Section: Current Strategies and Future Processes For Nems/mems-based ...mentioning

confidence: 99%

“…Researchers are designing NEMS/MEMS sensors that detect specific wavelengths of infrared radiation. This selective detection is helpful for applications like gas sensing, where different gases have distinct infrared absorption spectra. , …”

Section: Current Strategies and Future Processes For Nems/mems-based ...mentioning

confidence: 99%

Recent Developments in Wearable NEMS/MEMS-Based Smart Infrared Sensors for Healthcare Applications

Padha,

Yadav,

Dutta

et al. 2023

ACS Appl. Electron. Mater.

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Incorporating nano-and microelectromechanical systems (NEMS/MEMS)-based sensors in clothing and developing more compact and flexible devices have gained popularity recently. NEMS/MEMS-based bolometers/sensors have gained significance due to their high sensitivity and accuracy in measuring physical parameters such as temperature, humidity, pressure, and infrared (IR) and ultraviolet (UV) radiations. When worn on the body, bolometers can be employed in various applications such as environmental monitoring or health tracking. This review highlights the progress of smart wearable bolometers as NEMS/ MEMS-based sensors in the healthcare industry. Instead of visiting multiple healthcare facilities or devices, now people can assess their health status by measuring body temperature, sensing motion, respiratory functioning, blood pressure, oxygen levels of the blood, and heart functioning by integrating these devices into fabriclike garments, socks, shoe insoles, wrist watches, and other pieces of clothing. The article concludes by describing their varied challenges and possible solutions and prospects.

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“…It is imperative to incorporate biosensor components into a device that can load samples and reagents simultaneously and detect signals in an automated format called lab-on-a-chip (LOC) [13]. In an effort to nd new paths for improving diagnosis and treatment, this study explores the relationship between sensor research, technology, and a number of high-mortality malignancies (including colorectal, prostate, breast, and lung cancers).…”

Section: Introductionmentioning

confidence: 99%

Development of a MEMS-Based Biosensor for Analyzing the Bio-Electrical Characteristics of Colon Cancer Cells

shameem

2024

Preprint

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Investigating the bioelectrical characteristics of individual cells can provide important information about many aspects of cellular processes and their roles in general health and disease conditions. Comprehending these attributes at the cellular level facilitates a more intricate comprehension of physiological mechanisms and creates novel opportunities for disease detection, management, and even averting. It's fascinating to observe how new methods and technological developments are allowing us to learn more about the intricacies of cellular biology and how they relate to human health. Since cancer cells have slightly lower capacitance and resistance values, the bioelectrical properties could be used as biomarkers for early cancer identification. Measurements were conducted on the capacitance and resistance of individual normal cell lines (IEC-6), and highly-invasive malignant (SW480) colon cancer cells using MEMS sensors during simulations. Normal cell resistance is 318kΩ, while normal cell capacitance is 8.12nF. These values differ from those of cancer cells, which have variable resistance and capacitance values (246kΩ and 3.91nF for SW480). At a frequency range of 200 Hz to 2 MHz significant difference is observed in impedance magnitude response values between normal cells (7.7 MΩ to 62kΩ) and cancer cells (7.1 MΩ to 54.9kΩ).

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Current nanotechnology advances in diagnostic biosensors

Cited by 30 publications

References 284 publications

Lipid-based nanoparticles as drug delivery carriers for cancer therapy

Lipid-based nanoparticles as drug delivery carriers for cancer therapy

Recent Developments in Wearable NEMS/MEMS-Based Smart Infrared Sensors for Healthcare Applications

Development of a MEMS-Based Biosensor for Analyzing the Bio-Electrical Characteristics of Colon Cancer Cells

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