Current opinion: advances in machine perfusion and preservation of vascularized composite allografts – will time still matter?
Tessa E. Muss,
Amanda H. Loftin,
Byoung Chol Oh
et al.
Abstract:Purpose of review
A major hurdle hindering more widespread application of reconstructive transplantation is the very limited cold ischemia time (CIT) of vascularized composite allografts (VCAs). In this review, we discuss cutting edge machine perfusion protocols and preservation strategies to overcome this limitation.
Recent findings
Several preclinical machine perfusion studies have demonstrated the multifactorial utility of this technology to extend p… Show more
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