Current therapeutic options for low‐risk papillary thyroid carcinoma: Scoping evidence review

Abstract

Most cases of thyroid carcinoma are classified as low risk. These lesions have been treated with open surgery, remote access thyroidectomy, active surveillance, and percutaneous ablation. However, there is lack of consensus and clear indications for a specific treatment selection. The objective of this study is to review the literature regarding the indications for management selection for low‐risk carcinomas. Systematic review exploring inclusion and exclusion criteria used to select patients with low‐risk carcinomas for treatment approaches. The search found 69 studies. The inclusion criteria most reported were nodule diameter and histopathological confirmation of the tumor type. The most common exclusions were lymph node metastasis and extra‐thyroidal extension. There was significant heterogeneity among inclusion and exclusion criteria according to the analyzed therapeutic approach. Alternative therapeutic approaches in low‐risk carcinomas can be cautiously considered. Open thyroidectomy remains the standard treatment against which all other approaches must be compared.

Reminiscence therapy care program as a potential nursing intervention to relieve anxiety, depression, and quality of life in older papillary thyroid carcinoma patients: A randomized, controlled study

“…The possible reason might be that: as mentioned above, RT-CP allowed older PTC patients to share wonderful memories with other patients, which would help patients to rebuild self-identity, enhance social ability, make new friends, and trigger the aspiration for a better life ( Liu and Li, 2021 ; Zhang et al, 2021 ; Zhao, 2021 ); all of these helped them to build a positive attitude towards life, and might further improve the quality of life. ( Sanabria et al, 2022 ) RT-CP could also enhance the function score to some extent. The possible explanation would be that: as discussed above, RT-CP could improve patients’ mental health by recalling and sharing pleasant memories with others, which helped them to restore emotional, cognitive, and social functions; additionally, RT-PC also provided health education, which might assist patients in restoring physical and role functions ( Liu and Li, 2021 ; Zhao, 2021 ; Zhou and Sun, 2021 ; Li et al, 2022 ).…”

“…This study discovered that anxiety and depression were attenuated to some extent in the RT-CP group compared with the U-CP group. The potential reasons might be that: ( Megwalu and Moon, 2022 ) RT-CP encouraged older PTC patients to recall and share past positive memories, which would make them feel valued and connected ( Liu and Li, 2021 ; Zhao, 2021 ; Sanabria et al, 2022 ) older PTC patients were likely to develop negative emotions, such as lonely, abandoned, unhappy, self-isolated, etc., while RT-CP allowed them to share pleasant memories with others, which helped these patients to regain hope, confidence, and self-esteem, thus helping them to have an optimistic mindset towards life ( Li et al, 2022 ). Thereby RT-CP could eliminate anxiety and depression to some extent in older PTC patients.…”

“…Currently, the primary treatment strategy for PTC patients is surgery (including lobectomy, thyroidectomy, neck dissection, etc. ; McDow et al, 2021 ; Ngo et al, 2021 ; Sanabria et al, 2022 ); followed by thyroid hormone therapy, radioactive iodine therapy, targeted therapy, etc. ( Kim et al, 2020 ; Hescheler et al, 2021 ; Chan and Kwong, 2022 ).…”

The Necessity of Lymph Node Dissection Between Sternocleidomastoid and Sternohyoid Muscles in pN1b Papillary Thyroid Carcinoma

“…Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy, and accounts for nearly 90% of differentiated thyroid carcinomas ( 1 ). Lymph node (LN) metastasis usually develops in PTCs, with a reported incidence of up to 90% ( 2 – 4 ). Routine central neck LN dissection is required for all PTC patients in China, while lateral neck dissection is performed for pathologically positive lateral LN ( 5 ).…”

Establishing a predictive model of hypoparathyroidism after total thyroidectomy and central lymph node dissection for postoperative calcium supplementation selectively

“…PTC is the most common pathological type of thyroid carcinoma, accounting for about 80% of all thyroid carcinomas (4). At present, PTC is treated with open surgery, remote access thyroidectomy, percutaneous ablation, and regular review (5), with open surgery being the predominant treatment. Surgical methods include total thyroidectomy (TT)/subtotal thyroidectomy (ST) and central lymph node dissection (CLND) (6).…”