2018
DOI: 10.5603/gp.a2018.0120
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Current treatment options for advanced choriocarcinoma on the basis of own case and review of the literature

Abstract: Choriocarcinoma is one of rare neoplasms of female reproductive organs. In the last decade only a few cases of this disease have been registered in Poland. The paper presents the current principles of diagnosis and treatment options for this rare disease based on the authors' clinical experience (description of the case) and literature review. This paper provides basic information on epidemiology, FIGO classification, and also discusses the chemotherapy regimens used in the medical treatment of choriocarcinoma… Show more

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Cited by 14 publications
(10 citation statements)
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“…patients diagnosed with metastases in other organs. 7,8 The International Federation of Gynecology and Obstetrics (FIGO) 2015 Cancer Report proposed an ultra high-risk GTN category based on the following criteria: FIGO prognosis score !12 points and liver or brain metastasis or patients with extensively transferred GTN. 9 Ultra highrisk GTN patients are classified because of poor treatment and high mortality.…”
Section: Discussionmentioning
confidence: 99%
“…patients diagnosed with metastases in other organs. 7,8 The International Federation of Gynecology and Obstetrics (FIGO) 2015 Cancer Report proposed an ultra high-risk GTN category based on the following criteria: FIGO prognosis score !12 points and liver or brain metastasis or patients with extensively transferred GTN. 9 Ultra highrisk GTN patients are classified because of poor treatment and high mortality.…”
Section: Discussionmentioning
confidence: 99%
“…The literature advises that early diagnosis and treatment can significantly improve the prognosis of this disease[ 14 ]. In this case brain metastases were already present at time of diagnosis, which worsened the long-term prognosis of the choriocarcinoma.…”
Section: Discussionmentioning
confidence: 99%
“…The prognosis of choriocarcinoma is related to clinical stage and trophoblastic activity (1,2). Treatment of choriocarcinoma may include chemotherapy radiation therapy or combination therapy (29,30).…”
Section: Discussionmentioning
confidence: 99%
“…Choriocarcinoma is a highly malignant tumour that develops from trophoblast cells and usually occurs in the uterus, and it can cause severe local damage and metastasize to other areas of the body (1). As the clinical presentation of choriocarcinoma may vary, diagnosis may be challenging and the prognosis of patients with choriocarcinoma is related to the clinical stage and trophoblastic activity (1,2).…”
Section: Introductionmentioning
confidence: 99%
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