Current Trends in the Clinical Approach of Idiopathic Short Stature in Children: Focus on Growth Hormone Therapy and Diagnostic Challenges

Abstract

Objective: This literature review article addresses idiopathic short stature in children, highlighting the diagnostic complexity and the importance of personalized clinical and therapeutic approaches. Method: The research, which selected 15 articles between 2018 and 2023 in PubMed Central, highlights clinical assessment, involving anthropometric parameters, medical history and advanced exams, such as magnetic resonance imaging. Result: Growth hormone (GH) therapy is emphasized in the therapeutic approach, highlighting the importance of medication titration. Studies reveal improvements not only in physical growth, but also in psychosocial aspects in children undergoing GH treatment. Conclusion: Despite challenges in interpreting genetic tests, the conclusion highlights advances in clinical assessment. Although GH therapy is effective, issues such as titration and identification of ideal patients remain under discussion. The summary emphasizes the need for individualized approaches and points out gaps to be explored in future research, reinforcing the importance of a comprehensive and specific vision in the management of idiopathic short stature in children.