2023
DOI: 10.25005/2074-0581-2023-25-4-541-552
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Current Views on the Pathogenesis and Early Diagnosis of Actinic Keratosis

SYDIKOV A.A.,
PYAGAY G.B.,
PYAGAY O.G.

Abstract: The article provides an overview of the epidemiology and pathogenesis of actinic keratosis (AK) and its clinical differentiation from cutaneous squamous cell carcinoma (SCC). The authors present varying perspectives on the prognosis of the disease's development and its pathogenetic link to SCC, highlighting the significance of early diagnosis of the malignant transformation. Researchers suggest several markers, such as p16, p53, and p63, to identify the malignant transition in its early stages. The authors sup… Show more

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