Curved sensors for compact and high-performance imaging systems (Conference Presentation)

Joaquina, Kelly; Hugot, Emmanuel; Behaghel, Thibault; Lombardo, Simona; Muslimov, Eduard

doi:10.1117/12.2557782

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“…One such technological development is curved detectors: while they are widespread in the biological world, in the form of the eye's retina [15], curved numerical sensors are a relatively new innovation [14]. Their use can lead to a reduced number of optical elements and lower aberrations in a given optical system [26,31], with applications ranging from telescopes [12], satellites [22] and cell phone cameras [25], where space is at a premium, to ultraviolet imaging [13], where a significant fraction of incoming light is absorbed by optical elements. In addition to simplifying some optical systems, curved detectors can also be used to properly image a curved objects.…”

Section: Introductionmentioning

confidence: 99%

High resolution, wide field optical imaging of macaque visual cortex with a curved detector

et al. 2022

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Objective. Cortical activity can be recorded using a variety of tools, ranging in scale from the single neuron (microscopic) to the whole brain (macroscopic). There is usually a trade-off between scale and resolution; optical imaging techniques, with their high spatio-temporal resolution and wide field of view, are best suited to study brain activity at the mesoscale. Optical imaging of cortical areas is however in practice limited by the curvature of the brain, which causes the image quality to deteriorate significantly away from the center of the image. Approach. To address this issue and harness the full potential of optical cortical imaging techniques, we developed a new wide-field optical imaging system adapted to the macaque brain. Our system is composed of a curved detector, an aspherical lens and a ring composed of LEDs providing uniform illumination at wavelengths relevant for the different optical imaging methods, including intrinsic and fluorescence imaging. Main Results. The system was characterized and compared with the standard macroscope used for cortical imaging, and a 3-fold increase of the area in focus was measured as well as a 4-fold increase in the evenness of the optical quality in vivo. Significance. This new instrument, which is to the best of our knowledge the first use of a curved detector for cortical imaging, should facilitate the observation of wide mesoscale phenomena such as dynamic propagating waves within and between cortical maps, which are otherwise difficult to observe due to technical limitations of the currently available recording tools.

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