Abstract:Introduction. Significant cranial defects result from a decompressive
craniectomy following head trauma, malignant edema of the brain or
intracranial hemorrhage, or resection of tumor affected bone. Unrepaired
cranial defects are not just a tremendous esthetical problem. The underlying
brain is unprotected, prone to injury, and this state can lead to the
so-called ?syndrome of the trephined? with mood instability, headaches, and
even a neurological deficit. Currently, there is no widely accep… Show more
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