Cutaneous Effects of Smoking

Freiman, Anatoli; Bird, Garrett; Metelitsa, Andrei I.; Barankin, Benjamin; Lauzon, Gilles J.

doi:10.1007/s10227-005-0020-8

Cited by 140 publications

(79 citation statements)

References 113 publications

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“…The relationship between cigarette smoking and postoperative complications is well established in the literature, such as infection of surgical wound (SW), graft necrosis or incisional hernias [2][3][4][5]20 . Soresen et al 21 reports that smoking is associated with SW infection at all types of surgery, with an odds ratio (OR) of 2,95 for SW infections in light smokers and an OR of 3,46 for heavy smokers.…”

Section: Discussionmentioning

confidence: 99%

“…Several studies have pointed out this phenomenon in cutaneous circulation, either by Doppler ecography of smokers 4 or by flow study of skin flaps 12 . As a result, the tissue oxygenation and aerobic metabolism will be adversely affected 12 .…”

Section: Discussionmentioning

confidence: 99%

“…There are many clinical trials and meta-analyses showing that smokers who underwent surgical events had more post operatory complications comparing to non smokers or smokers who had a bigger cessation time before and after surgery [1][2][3][4] .…”

Section: Introductionmentioning

confidence: 99%

“…This could predispose one who is undergoing surgery to complications such as infections, necrosis, delayed or anomalous wound healing, incisional hernia, among others [4][5][6] . Black et al 7 used human skin grafts to show that the presence of short-term nicotine amplified the concentration-dependent dermal vasoconstrictor effect of norepinephrine (NE) and attenuated endothelium-dependent skin vasorelaxation induced by acetylcholine in NE-preconstricted skin vasculature, without affecting endothelium-independent vasorelaxation induced by nitroglycerine in NE-preconstricted dermal vasculature.…”

Section: Introductionmentioning

confidence: 99%

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The effects of passive tobacco smoking on the microcirculation of the abdominal wall in rats

et al. 2016

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Brazil. Scientific, intellectual, conception and design of the study; analysis and interpretation of data, critical revision, final approval. ABSTRACT PURPOSE:To analysis the effects of passive smoking on the microstructure of tissues of the abdominal wall regarding microcirculation, using histopathological study of the tobacco exposed rats. METHODS: Twenty four male Wistar rats were divided in Control Group (CG = 8 animals) and Exposition Groups (EG = 16 animals).EG was exposed to cigarette smoke 4x/day for 120 days, while CG was preserved from exposure. Food, water and housing were similar for both groups. After 120 days, urine samples were collected before necropsy to analyze cotinine levels (ng/mL) in urine and blinded histopathological analysis of the abdominal wall performed to count arteries and veins in dermal and muscular fascia layer. RESULTS:No difference in weight was observed between both groups (P>0.05). Cotinine concentration was significantly higher in EG (P<0.05). In dermal layer, the average of vessels per animal was 8.72 (IC95%: 8.31-9.13) for CG and 11, for EG. In muscular fascia layer the average of vessels per animal was ) for CG, whereas the average for EG was of 14,85 (IC95%: 12.71-17.01) (P<0.05). CONCLUSION:Exposition to passive smoking may cause increase in the number of vessels in dermal layer, with the opposite effects at the muscular fascia layer.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The effects of passive tobacco smoking on the microcirculation of the abdominal wall in rats

et al. 2016

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“…Exposure can also lead to more serious dermatological issues such as atopic dermatitis, psoriasis, and even skin cancer. Pollutants can also weaken the skin barrier function and penetrate through the skin, causing systemic toxicity in other organs [8][9][10][11].…”

Section: Introductionmentioning

confidence: 99%

The Impact of Pollution on Skin and Proper Efficacy Testing for Anti-Pollution Claims

et al. 2018

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Exposure to pollution can cause oxidative stress, premature ageing, inflammation, and diseases. Since most of us are exposed to pollution, protection is important. This can be achieved through skin protection or through protection with respect to food and food supplements. There is a wide range of products on the market with anti-pollution claims. However, it is important that these claims are thoroughly validated by proper efficacy testing. When skin cells are exposed to pollution factors, changes in a number of skin properties can be observed, such as lipid composition, lipid and protein oxidation, pH, sebum secretion rate, oxidative stress, inflammation markers, and collagen and elastin levels. These can be measured and used as markers to verify anti-pollution claims. In the present review, we summarize some of the most important in vitro and in vivo tests that are used to determine if an ingredient or formulation has anti-pollution efficacy.

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Smoking and Skin Aging in Identical Twins

Doshi

Hanneman

Cooper³

2007

Arch Dermatol

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Background: A twin pair can provide a rare opportunity to control for genetic susceptibility and exposure variables, which often serve as major confounders in population-based studies on the relationship between smoking and skin aging.Observations: We describe a unique twin pair who spent not only their first 2 decades of life together but also in their later decades had the same type of job at the same latitude, resulting in well-matched levels of significant sun exposure. However, the twins differed markedly in regard to smoking history; the twin with an approximately 52.5-pack-year smoking history showed more severe skin aging than did the nonsmoking twin. Conclusion:The difference in skin aging illustrated by this twin pair may serve as a motivator for smoking cessation.

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Cutaneous Effects of Smoking

Abstract: An appreciation of the adverse cutaneous consequences of smoking is important. Dermatologists can play an integral role in promoting smoking cessation by providing expert opinion and educating the public on the deleterious effects of smoking on the skin.

Cited by 140 publications

References 113 publications

The effects of passive tobacco smoking on the microcirculation of the abdominal wall in rats

The effects of passive tobacco smoking on the microcirculation of the abdominal wall in rats

The Impact of Pollution on Skin and Proper Efficacy Testing for Anti-Pollution Claims

Smoking and Skin Aging in Identical Twins

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