Cutaneous leishmaniasis in a returning UK traveller

Raghunath, Rakhi Singh; Yong, Adrian Sze Wai; Igali, Laszlo; Tan, E.; Lockwood, Diana N J

doi:10.1136/postgradmedj-2014-132620

Cited by 1 publication

(1 citation statement)

References 3 publications

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“…Management strategy was described in 603 patients: 521 (86.4%) received systemic treatment, 42 (7.0%) local treatment, 6 (1.0%) combined local and systemic treatment and 34 (5.6%) no treatment (Table 7). A total of 85 failures or relapses were reported, representing 14.1% of cases [20,30,69,77,82,92,96,97,100,116,120,121,125,126,128,129,139,140,146,150,165,173,[177][178][179][180]194,228,269]. When retreatment was described (n = 44, [30,82,92,96,97,100,116,120,121,125,126,128,129,139,140,146,150,173,177-180, 194,228,269]), it most often consisted of a different strategy and/or drug (92.3%, [30,82,92,96,97,100,116,120,121,125,126,128,129,139,140,146,…”

Section: Clinical Aspects and Management Of Cutaneous Leishmaniasismentioning

confidence: 99%

Non-Endemic Leishmaniases Reported Globally in Humans between 2000 and 2021—A Comprehensive Review

Rocha¹,

Pereira

Maia³

2022

Pathogens

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Leishmaniases are human and animal parasitic diseases transmitted by phlebotomine sand flies. Globalization is an important driver of the burden and in the current dynamics of these diseases. A systematic review of articles published between 2000 and 2021 was conducted using the PubMed search engine to identify the epidemiology and clinical management of imported human leishmaniases as a fundamental step to better manage individual cases and traveler and migrant health from a global perspective. A total of 275 articles were selected, representing 10,341 human imported cases. Identified drivers of changing patterns in epidemiology include conflict and war, as well as host factors, such as immunosuppression, natural and iatrogenic. Leishmania species diversity associated with different clinical presentations implies diagnostic and treatment strategies often complex to select and apply, especially in non-endemic settings. Thus, diagnostic and management algorithms for medical clinical decision support are proposed. Increased surveillance of non-endemic cases, whether in vulnerable populations such as refugees/migrants and immunocompromised individuals or travelers, could improve individual health and mitigate the public health risk of introducing Leishmania species into new areas.

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