Cutaneous metastasis from solid organ cancer: A histopathological and immunohistochemical study of 74 cases from a tertiary care centre of North India

Retrospective review of cutaneous metastasis among 11,418 patients with solid malignancy

“…The present and previous studies have shown that CM is more common from adenocarcinoma than other histological types of cancer [2,4,8,10–15] . This may also be associated with breast cancer prevalence, as the most common cancer type with CM.…”

“…[7] The rate of CM from breast cancer varied from 18.6% to 26.5% in some studies and was higher than in other cancers. [8,[10][11][12][13][14][15] This can be explained by breast cancer 's superficial location and its direct contiguity with the overlying skin. [16] Furthermore, the site of CM tends to occur close to the region of primary cancer.…”

“…The present and previous studies have shown that CM is more common from adenocarcinoma than other histological types of cancer. [2,4,8,[10][11][12][13][14][15] This may also be associated with breast cancer prevalence, as the most common cancer type with CM. Another possibility is the "seed and soil hypothesis," stating that the skin may provide a favorable environment for certain cancer cells.…”

“…Breast cancer is the most common primary cancer with CM, while the anterior chest wall is the most frequently found CM site [7] . The rate of CM from breast cancer varied from 18.6% to 26.5% in some studies and was higher than in other cancers [8,10–15] . This can be explained by breast cancer ‘s superficial location and its direct contiguity with the overlying skin [16] .…”

Management of a glottic squamous cell carcinoma with cutaneous metastasis

“…4 In literature, retrospective analysis has conflicting results. While breast and gastrointestinal cancers were reported to be the most common primaries, 5 El Khoury et al found that the most common primary cancer was breast cancer in women and laryngeal cancer in men. 6 There are extremely rare cases of CM of GC in the literature.…”