Cutaneous Metastatic Carcinoma

Abstract

Cutaneous metastatic carcinoma exhibited a pattern of clinical significance. Clinicians are urged to renew interest in cutaneous nodules, chronic discharging sinuses, and ulcers.

Cutaneous Metastatic Disease: Case Series in a Tropical Setting

“…Cutaneous metastases arising from carcinomas though rare are important findings in clinical practice [1] [2]. It is reported to occur in 0.7% -5% of cancer patients [3], some have reported up to 9% [4], and others 10.4% [5].…”

“…Cutaneous metastasis is very rare in children and varies according to sex. Metastasis from the colon including lungs is common in males while that from the breast commoner in females [1] [2]. Clinical findings may be barely noticeable and require a high index of suspicion [2].…”

“…Clinical findings may be barely noticeable and require a high index of suspicion [2]. Skin metastasis presents commonly as skin nodules (single or multiple), usually painless and may mimic dermatofibroma, neurofibroma, lipoma and granuloma [1] [2] [8]. Some malignancies have a predilection for areas of metastasis, which can be useful in directing search for the primary site [2].…”

“…Some malignancies have a predilection for areas of metastasis, which can be useful in directing search for the primary site [2]. Presentation is classified into the following settings: a) develop after initial diagnosis of primary malignancy, b) carcinoma of unknown primary site (CUPS), c) detected as the same time of diagnosis [1] [2]. Diagnosis is based on histology and the pattern provides clue to the location of the primary malignancy [1].…”

“…Presentation is classified into the following settings: a) develop after initial diagnosis of primary malignancy, b) carcinoma of unknown primary site (CUPS), c) detected as the same time of diagnosis [1] [2]. Diagnosis is based on histology and the pattern provides clue to the location of the primary malignancy [1]. In addition, immunohistochemistry provides a useful adjunct in directing search of the primary tumour [2] [9].…”