Cutaneous pseudolymphoma: An enigma

Shashikumar, BM; Harish, MR; Katwe, KirtiP; Kavya, M

doi:10.4103/wkmp-0150.196949

Cited by 2 publications

(6 citation statements)

References 1 publication

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“…In cases of suspected cutaneous PSL, excluding the possibility of malignancy is of utmost importance [4], [8]. The diagnosis must always be made based on the combination of clinical and histopathological examination and often requires additional examinations such as immunohistochemistry and molecular biological examination [7], [9]. Clinically, most PSL cases manifest as solitary erythematous to brown or purplish plaque with facial predilection; however, it can also appear as solitary to multiple papules or infiltrated plaques [4].…”

Section: Discussionmentioning

confidence: 99%

“…(T-PSL), and PSL with mixed and unclassified infiltrate [2], [7]. In immunohistochemical examination, most infiltrates are represented by more or dominant B-cell markers than T-cell markers [1].…”

Section: Pathologically Cutaneous Psl Is Classified Into Ordinary Psl (O-psl) Psl With Dominant B-cell Infiltrates (B-psl) Psl With Dominmentioning

confidence: 99%

“…Antigens in cutaneous PSL can be in the form of insect bites, tattoos, trauma, vaccinations, jewelry, drugs, and infection by B. burgdorferi. In many cases, the etiology of PSL cannot be unveiled and, therefore, can be classified as an idiopathic case [7], [8], [9].…”

Section: Pathologically Cutaneous Psl Is Classified Into Ordinary Psl (O-psl) Psl With Dominant B-cell Infiltrates (B-psl) Psl With Dominmentioning

confidence: 99%

“…In other reports, treatment with topical and/or intralesional corticosteroids resulted in improvement in the skin disease [3]. Lesions of PSL were treated with intralesional triamcinolone acetonide injection 10 mg/ml for 2 sittings, 3 weeks apart following which resulted in complete remission of the nodules without any relapse on follow-up [7].…”

Section: Pathologically Cutaneous Psl Is Classified Into Ordinary Psl (O-psl) Psl With Dominant B-cell Infiltrates (B-psl) Psl With Dominmentioning

confidence: 99%

“…scabies), insect bites, injection of vaccines, or desensitization antigens, foreign bodies such as tattoos and metals, and drugs have been identified as causative factors for PSL. All cases without identifiable causes are called idiopathic PSL [1], [5], [6], [7].…”

Section: Introductionmentioning

confidence: 99%

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Cutaneous B-Cell Pseudolymphoma Successfully Treated with Triamcinolone Acetonide

Anggraeni

Sumarheni

Tabri

et al. 2021

Open Access Maced J Med Sci

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BACKGROUND: Cutaneous pseudolymphoma (PSL) is a reactive polyclonal benign lymphoproliferative process in the skin that simulate cutaneous lymphomas clinically, histologically, or both, predominantly composed of either B-cells or T-cells, localized or disseminated. PSL clinically manifests as solitary nodules or plaque on the face. In cases where cutaneous PSL is suspected, the most crucial part is diagnosis, to differentiate benign or malignant lesion. Diagnosis required a combination of clinical, histopathological, and immunohistochemistry examination. CASE REPORT: A 59-year-old man presented with asymptomatic erythematous plaque on her cheek for 6 months before. Histopathological examination revealed dense small lymphocytic infiltration forming lymphoid follicles with centrum germinativum that partially destructed skin appendice glands. Immunohistochemistry examination showed positive result on cluster of differentiation (CD)20 and CD3 staining. With domination of CD20 treatment: Patient was treated with intralesional injection of triamcinolone acetonide 10 mg/ml and showed satisfying result after 3 times injection. CONCLUSION: A cutaneous B-cell PSL in a 59-year-old man was diagnosed based on history and physical, histopathological, and also immunohistochemistry examination. Intralesional injection of 10 mg/ml triamcinolone acetonide gave satisfying result.

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Section: Discussionmentioning

confidence: 99%

Section: Pathologically Cutaneous Psl Is Classified Into Ordinary Psl (O-psl) Psl With Dominant B-cell Infiltrates (B-psl) Psl With Dominmentioning

confidence: 99%

Section: Pathologically Cutaneous Psl Is Classified Into Ordinary Psl (O-psl) Psl With Dominant B-cell Infiltrates (B-psl) Psl With Dominmentioning

confidence: 99%

Section: Pathologically Cutaneous Psl Is Classified Into Ordinary Psl (O-psl) Psl With Dominant B-cell Infiltrates (B-psl) Psl With Dominmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Cutaneous B-Cell Pseudolymphoma Successfully Treated with Triamcinolone Acetonide

Anggraeni

Sumarheni

Tabri

et al. 2021

Open Access Maced J Med Sci

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A Rare and Fatal Case of Cutaneous T-Cell Lymphoma (CTCL)

Sasmithae¹,

Perdana²

2021

Indonesian Journal of Cancer

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Introduction: Cutaneous T-Cell Lymphoma (CTCL) is a form of Non-Hodgkin Lymphoma involving T-cell neoplasms mainly concentrated in the skin. Primary Cutaneous Peripheral T-Cell Lymphoma is Not Otherwise Specified (PTL-NOS) is the rarest case of CTCL disease.Case Presentation: A female, 35 years old, complained of a lump on her face. In the last 3 months, the lump felt soft, contained a liquid that, when it ruptures, secretes Blood, and the crusty scar will blacken and easily bleed with pain. Physical examination of pale conjunctiva on the face, neck, chest, abdomen, back, and legs obtained nodules with a chewy consistency with erythema appearance in varying size. Some nodules that appear were covered in blackish crustae. The right lung has a decrease in the sound of breath, accompanied by swelling in both limbs. The conclusion of bilateral femur skin biopsy impresses cutaneous T lymphoma cells. Within three months, cancer developed into lesions spread almost throughout the body, and due to the rapid and progressive nature of cancer, its diagnosis developed into PTL-NOS.Conclusions: Patients with PTL-NOS may come with solitary nodules such as red tumors in any area of the body. However, most often, patients come with symptoms of multifocal or diffuse scattered nodules. In enforcing the diagnosis, it takes a high level of suspicion, and multiple rebiopsies are necessary to enforce the diagnosis of CTCL.

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Cutaneous pseudolymphoma: An enigma

Cited by 2 publications

References 1 publication

Cutaneous B-Cell Pseudolymphoma Successfully Treated with Triamcinolone Acetonide

Cutaneous B-Cell Pseudolymphoma Successfully Treated with Triamcinolone Acetonide

A Rare and Fatal Case of Cutaneous T-Cell Lymphoma (CTCL)

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