Cutaneous Sarcoidosis-like Eruption Following Second Dose of Moderna mRNA-1273 Vaccine: Case or Relationship?

Abstract

Various adverse reactions to SARS-CoV-2 vaccines have been described since the first months of the vaccination campaign. In addition to more frequent reactions, rare reactions, such as sarcoidosis-like, rashes have been reported. We present a case of a 23-year-old woman with a rash on the chin and peribuccal region, which developed approximately 3 weeks after the administration of the second dose of the Moderna mRNA-1273 vaccine. We briefly discuss other reports in the literature.

Annular cutaneous sarcoidosis following COVID‐19 vaccination

“…To the best of our knowledge, there are four other published cases of cutaneous sarcoidosis after COVID-19 vaccination. [7][8][9][10] However, interestingly, our case is the first description of cutaneous sarcoidosis initiated at the vaccination site. The present case suggests a causal relationship between the COVID-19 vaccine and cutaneous sarcoidosis, attending to the temporal association and the development of skin sarcoid reaction at the exact location of vaccine administration.…”