Cutaneous tuberculosis overview and current treatment regimens

Zyl, Lindi van; Plessis, Jeanetta du; Viljoen, Joe M.

doi:10.1016/j.tube.2014.12.006

Cited by 185 publications

(191 citation statements)

References 82 publications

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“…Based on the pathogenesis, clinical features and histopathology cutaneous TB is classified as:Inoculation TB from an exogenous source through a broken skin in a person who was previously not infected with TB.TB from an endogenous source such as lymph nodes, bones and joints.Haematogenous TB.12…”

Section: Discussionmentioning

confidence: 99%

Extrapulmonary tuberculosis: atypical presentation in otorhinolaryngology

Subramani¹,

Saravanam

Rajendran

2018

BMJ Case Reports

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Tuberculosis (TB) continues to be a major health burden globally more so in low/middle-income countries like India. There is an increase in the prevalence of extrapulmonary TB (EPTB) because of HIV epidemics and increased usage of immunomodulating drugs. EPTB constitutes 15%-20% of all patients with TB and >50% of HIV-TB coinfected patients. We present three such atypical presentations of EPTB in head and neck region. EPTB can mimic any disease, hence knowledge of the unusual presentations helps in making early diagnosis and thereby reduces the morbidity and mortality involved with the disease.

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Section: Discussionmentioning

confidence: 99%

Extrapulmonary tuberculosis: atypical presentation in otorhinolaryngology

Subramani¹,

Saravanam

Rajendran

2018

BMJ Case Reports

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“…Skrofuloderma, lupus vulgaris ile tüberkülozis kutis verrükozada antitüberküloz tedaviye ek olarak cerrahi eksizyon, kriyoterapi veya elektrokoterden yararlanılabilmektedir. 10,11 Olgumuzda da 2 ay dörtlü tedavi, 4 ay ikili tedavi uygulanıp, tedavi süresi 6 aya tamamlanmıştır. Tedavinin sonunda lezyonlarda skar ile tam iyileşme gözlenmiştir.…”

Section: Discussionunclassified

A Skin Tuberculosis Case: Scrofuloderma

Albayrak¹,

Karaali²,

Yanik³

et al. 2017

Turkiye Klinikleri J Intern Med

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eri tüberkülozu, etken mikobakterinin giriş yoluna, patojenitesine, konağın duyarlılığı ve hücresel immünitesine bağlı olarak farklı gö-rünümlerle ortaya çıkmaktadır. Skrofuloderma; endojen kaynaklı sekonder bir tüberkülozdur. Deri tüberkülozları içerisinde ikinci en sık görülen formdur. Genellikle çocuklar, genç erişkinler ve yaşlı hastalar etkilenmektedir.1-4 Dokudaki mikobakteri sayısının az olmasına bağlı olarak etken mikroorganizmanın her zaman gösterilememesi ve pürifiye protein derivesi (PPD), Ehrlich Ziehl Neelson (EZN) gibi diğer tanı yöntemlerinin de negatif olabilmesi nedeni ile tanı koymak her zaman kolay değildir. Bu nedenle birçok hasta farklı tanı ve tedavilerle uzun süre izlenebilmektedir. 5,6

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“…Cutaneous tuberculosis can be classified 112 as, inoculation tuberculosis from an exogenous source, tuberculosis from an endogenous source and haematogenous tuberculosis.…”

Section: Discussionmentioning

confidence: 99%

“…These infections are “inoculation” tuberculosis due to inadequately sterilised needles 112 in the M tuberculosis group and probable use of contaminated tapwater, 61 the major reservoir of rapidly growing mycobacteria (RGM) in the cluster of cases of Mycobacterium chelonae and Mycobacterium fortuitum.…”

Section: Discussionmentioning

confidence: 99%

Sepsis, parenteral vaccination and skin disinfection

Cook

2016

Human Vaccines & Immunotherapeutics

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ASBSTRACTDisinfection should be required for all skin penetrative procedures including parenteral administration of vaccines. This review analyses medically attended infectious events following parenteral vaccination in terms of their microbiological aetiology and pathogenesis. Like ‘clean’ surgical site infections, the major pathogens responsible for these events were Staphylococcal species, implicating endogenous con-tamination as a significant source of infection. As 70% isopropyl alcohol swabbing has been shown to effectively disinfect the skin, it would be medico-legally difficult to defend a case of sepsis with the omission of skin disinfection unless the very low risk of this event was adequately explained to the patient and documented prior to vaccination. There was a significant cost-benefit for skin disinfection and cellulitis. Skin disinfection in the context of parenteral vaccination represents a new paradigm of medical practice; the use of a low cost intervention to prevent an event of very low prevalence but of significant cost.

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Cutaneous tuberculosis overview and current treatment regimens

Cited by 185 publications

References 82 publications

Extrapulmonary tuberculosis: atypical presentation in otorhinolaryngology

Extrapulmonary tuberculosis: atypical presentation in otorhinolaryngology

A Skin Tuberculosis Case: Scrofuloderma

Sepsis, parenteral vaccination and skin disinfection

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