Cyclic configuration of the aspartate ion in the crystal structure of zinc, cobaltous and nickelous aspartate trihydrate

Doyne, Thomas H.; Pepinsky, R.; Watanabe, Tomohiro

doi:10.1107/s0365110x57001449

Cited by 43 publications

(15 citation statements)

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“…The preliminary coordinates of the main atoms are given in Table 33. More precise data have been obtained from the isomorphous salts ot L-aspartic acid with Zn z +, Co z +, and Niz+ [72], which crystallize as trihydrates with space group P2 1 2 1 2 1 and the following cell parameters: Doyne and Pepinsky deduced the absolute configuration for the cobalt salt on the basis of anomalous x-ray scattering. The resulting coordinates were assigned to the zinc salt and then were refined by least squares from the three-dimensional set of intensities.…”

Section: Monoaminodicarboxylic Acidsmentioning

confidence: 99%

The Molecular Structure of Amino Acids

Gurskaya

1995

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Section: Monoaminodicarboxylic Acidsmentioning

confidence: 99%

The Molecular Structure of Amino Acids

Gurskaya

1995

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“…The zinc, nickel, and cobalt salts were first reported by Doyne et al (1957), who only gave the unit cell dimensions. As later works established the structure for the zinc (Kryger and Ramsussen 1973;Zhang et al 2004) and the manganese analog Sekizaki (1979) 3.8 Asparagine, Glutamine, Aspartic Acid, and Glutamic Acid (Schmidbaur et al 1988), the agreement of the unit cell dimensions allows the conclusion that all four salts crystallize in the same structure.…”

Section: Tris(l-cysteinato-s)-bismuth Monohydrate Comprises [3]-coordmentioning

confidence: 98%

Compounds of Amino Acids as Anions

Fleck

Petrosyan

2014

Salts of Amino Acids

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This chapter deals with salts formed from metal cations and amino acid anions. All amino acids can act as monovalent anion; the acidic members glutamic acid and aspartic acid as well as cysteine and tyrosine can form both monovalent and divalent anions. Due to the large number of available cations, a multitude of combinations is possible and in fact found (for the standard twenty amino acids, over 150 crystal structures are published, and many more species have been characterized by other methods). Different hydration states (as reported for the pristine amino acid crystals) occur as well, and the existence of polymorphs is also documented for some cases. The formation of metal-amino acid complexes has been studied in several works (both for a given amino acid and a given cation), and the flexibility of amino acid molecules as ligands allows coordination of cations with different chemical properties (such as charge or ionic radius). Several coordination modes are found for amino acids -the molecules can act as monodentate, bidentate, tridentate, and bridging ligands. The connectivity of the coordination polyhedra of the metal cations is considered -isolated units are frequent, but chains and layers occur as well. Moreover, these units can connect via amino acid molecules to form higher-dimensional structures. Hydrogen bonds (also involving water molecules, both in coordination or in the interstices as crystal water) further stabilize the units, forming relatively stable phases. The frequency of salts varies among the different amino acids, and most examples are reported for glycinate salts, whereas crystals of cations and basic and weakly soluble amino acids are difficult to obtain (e.g., arginate and lysinate salts have not been reported in crystalline state). Finally, the aspect of symmetry is considered (the chirality of most amino acids playing a crucial role), and, consequently, the properties of these salts have impact on applications in the fields of physics, biology, and medicine.

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“…However, the bond lengths and angles within the cobaltate anion in (I) are in good agreement with those found in other structures containing this type of anion such as, for example, those described by Oonish et al (1973Oonish et al ( , 1975 and several other related structures. In contrast, recourse to the Cambridge Structural Database (Version 5.26; Allen, 2002) by means of the Chemical Database Service of the EPSRC (Fletcher et al, 1996) has revealed only one example of a cobaltous aspartate species, namely cobaltous aspartate trihydrate, (II) (Doyne et al, 1957), which is polymeric, has a Co:asp ratio of 1:1 [as distinct from 1:2 in (I)] and displays different (slightly longer) Co-N and C-O bond distances from those observed in the cobaltate anion in (I). It seems reasonable to suggest that, had not oxidation of the Co II of the starting material to Co III taken place resulting in the formation of (I), then (II) might well have been the product of the reaction.…”

Section: Figurementioning

confidence: 99%