Cyclic peptides as chiral selectors in high-performance liquid chromatography

Birkinshaw, Fiona L.; Taylor, David R.; Goodall, David M.; Wu, Zecai; Lisseter, Stephen G.; Bevan, Christopher; Mutton, Ian M.; Hargrave, C. P.; Waters, David G.; Smith, I.; Simpson, C. F.

doi:10.1039/ap9922900235

Cited by 5 publications

(1 citation statement)

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“…Nevertheless, research on peptide and peptidomimetic chiral selectors has continued and significant progress has been made in recent years. Early work regarding peptide chiral selectors such as those from Grushka and Scott [7], Rogers et al [8,9], and Birkinshaw and Taylor [10] has been reviewed [11]. In this article, the use of combinatorial libraries to screen a large number of peptides and peptidomimetics for potential enantioselectivity, chiral diamide phases, and oligoproline-based chiral stationary phases are discussed.…”

Section: Introductionmentioning

confidence: 99%

Peptide and peptidomimetic chiral selectors in liquid chromatography

Li¹

2005

J of Separation Science

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The application of peptide and peptidomimetic chiral selectors in LC is reviewed in this article. In particular, methods for finding these types of selectors using combinatorial library approaches are discussed, as well as recent advances in the use of peptides and peptidomimetics as general chiral selectors for LC. In terms of the library approaches, batch screening and reciprocal screening are discussed. As for general chiral selectors, one example involves the application of chiral diamide phases. Another example shows the versatility of oligoproline chiral stationary phases, which exhibit resolution for a number of racemic analytes, comparable to other well-established chiral stationary phases.

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Section: Introductionmentioning

confidence: 99%

Peptide and peptidomimetic chiral selectors in liquid chromatography

Li¹

2005

J of Separation Science

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Recent advances in peptide chiral selectors for electrophoresis and liquid chromatography

Bluhm

Huang

2005

Anal Bioanal Chem

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The application of peptides in chiral separations using techniques such as capillary electrophoresis (CE), electrokinetic capillary chromatography (EKC) and liquid chromatography is the focus of this review. Methods for finding peptide selectors using combinatorial library approaches are discussed, as well as recent advances in the use of peptides as general chiral selectors for electrophoresis and liquid chromatography. One example shows the effectiveness of polymeric dipeptide surfactants as general chiral selectors for electrophoresis. Another example shows the versatility of oligoproline chiral stationary phases, exhibiting resolution for a number of racemic analytes comparable to other well-established chiral stationary phases.

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Proteins and peptides as chiral selectors in liquid chromatography

Allenmark

Andersson

1994

Journal of Chromatography A

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Cyclic peptides as chiral selectors in high-performance liquid chromatography

Cited by 5 publications

References 1 publication

Peptide and peptidomimetic chiral selectors in liquid chromatography

Peptide and peptidomimetic chiral selectors in liquid chromatography

Recent advances in peptide chiral selectors for electrophoresis and liquid chromatography

Proteins and peptides as chiral selectors in liquid chromatography

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