Cyclic polyamines via a molybdenum(0) templated Mannich-type reaction

Abstract

Reaction of [Mo(CO) 3 (3-azahexane-1,6-diamine)] with formaldehyde and the carbon acid nitroethane leads to cyclisation involving one terminal amine and either the internal secondary amine (minor product) or the other terminal primary amine (major product), with zinc/acid reduction yielding new cyclic tetraamines, also characterised as their cobalt(III) complexes. This is the first example of Mannich-style formation of a pendant-arm triazamacrocycle around a molybdenum(0) template. The unexpected N-(1¢-aminopropyl)-6-methyl-1,4-diazacycloheptan-6-amine minor product has been characterised by an X-ray structure as its cis-dichlorocobalt(III) complex.

Phosphate Ester Hydrolysis Promoted by an Amidopyridine Carboxylate Complex

“…This ligand was prepared according to the method described, 30 and characterized by spectroscopic comparison with an authentic sample.…”

“…The pH was maintained through the use of buffers (TRIS, phosphate, and hydroxide) and was prepared according to literature. 30 Rate constants at the various pH values are shown in Table-3. As seen from the table, generally, the rate constants increase as the pH increase up to pH ~9, then falls.…”