Cyclic Vomiting Syndrome Is Associated with Rapid Early Gastric Emptying

Spectrum of gastric emptying patterns in adult patients with cyclic vomiting syndrome

“…Similar results were noted by Fajardo et al. , using similar 2 h criteria 7 . They compared 64 CVS patients with 364 controls and showed a rapid early‐phase GE (gastric retention<30% at 2 h) in CVS patients with an odds ratio of 13 (95% CI 5–33) 7 .…”

“…, using similar 2 h criteria 7 . They compared 64 CVS patients with 364 controls and showed a rapid early‐phase GE (gastric retention<30% at 2 h) in CVS patients with an odds ratio of 13 (95% CI 5–33) 7 . The requirement for <50% retention at 1 h was not the criteria applied to these studies.…”

“…These tended to be studies with small numbers of patients without the use of established GE criteria for identifying rapid or slow rates of emptying. [6][7][8][9] Normal GE in a pediatric population using ultrasound method for measuring GE was noted. 10 There are also limited reports of slow GE in pediatric 11 and adult CVS populations.…”

Cyclic vomiting syndrome in adults

“…These individuals exhibit more severe gastric retention than those with chronic symptoms. However, as observed in recent studies, rates of gastric emptying often are accelerated rather than delayed in patients with CVS during the asymptomatic period when vomiting is absent allowing the test to be performed 14,16 …”

“…‘Gastric emptying’ and myoelectric activity have been investigated in adult patients with CVS, primarily during asymptomatic periods between emetic episodes. Two groups have documented the presence of rapid gastric emptying between attacks in adults with CVS 14,16 . In contrast, delayed gastric emptying during the vomiting phase was observed in some patients when this test was able to be performed 14 .…”