Cyclodextrin-dendrimers nanocomposites functionalized high performance liquid chromatography stationary phase for efficient separation of aromatic compounds

Yu, Shuxin; Sha, Xuming; Zhou, Xiaojin; Guo, Dandan; Han, Bowen; Huang, Shaohua; Zhu, Yan

doi:10.1016/j.chroma.2021.462730

Cited by 9 publications

(1 citation statement)

References 39 publications

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“…These hybrid dendrimers are used as a bioelectrode with detection limit 160 nm, sensitivity 602 µA m −1 cm 2 and during storage even in wet conditions it retained 63% of initial activity for around 30 days. [ 81 ] Cyclodextrin grafted dendrimer nanocomposites are widely in use for effective high resolution separation of aromatic compounds like alkyl benzene and benzenesulfonic acid present in the stationary phase of high performance liquid chromatography owing to the cavity like structure of cyclodextrin. [ 82 ]…”

Section: Introductionmentioning

confidence: 99%

Integration of Hybrid Dendrimers and Their Generations for Modulated Spatio‐Temporal Action

Kharangate

Shende

2023

Part & Part Syst Charact

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Hybrid dendrimers constitute a unique class of well-defined complex architecture featured with a central domain and bifurcated branches with two different dendritic sequences for their atomic configuration and functional groups at the periphery. This review article pioneers the field of new hybrid dendrimers using different generations by nanoconjugation with metals, carbohydrates, nucleotides, proteins/peptides, carbosilane, urea, silica, stem cells, guanidine, etc. The smart dendrimers contain desirable electrical, magnetic, optical, and biological attributes to increase surface area, monodisperse behavior, dose reduction, dissolution, permeability, longterm stability, and significant decrement in nanotoxicity studies. The higher encapsulation of lipid soluble and insoluble moieties explores an excellent platform for the delivery of drugs (ibuprofen, indomethacin, etc.), nucleic acids (oligonucleotide, siRNA, and aptamer), genetic materials , and chemical diagnostic agents (gadolinium chelates and superparamagnetic iron oxide particles) for imaging. Owing to their flexibility in structural adaptability, different health conditions like glaucoma, inflammation, microbial infection, neurodegenerative problems (Alzheimer's disease and Parkinsonism), and cancer are benefited using such long-lasting drug delivery. Advancements in molecular engineering techniques, 3D printing, artificial intelligence, robotic, green synthesis, and microwave-assisted methods aid in the development of economically reliable and personalized pharmaceutical hybrid dendritic systems resembling antibodies, globular proteins, stem cells, enzymes, and genetic materials.

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Section: Introductionmentioning

confidence: 99%