Cyclotides Versus Acyclotides: Discovery, Characterization and Their Potential in Cancer Therapy
Uyen N. P. Nguyen,
Son H. Pham,
Le Tien Dung
et al.
Abstract:Protein‐ and peptide‐based therapies have emerged as a possible alternative to antibody‐ and small molecule‐ based therapies for treating cancer, aiming to improve drug localization and enhance effectiveness. Peptides such as cyclotides and acyclotides are known for their exceptional stability, which is attributed to the presence of a cystine knot. These peptides exhibit a diverse array of biological activities, making them promising candidates for therapeutic development. Transcriptomics approaches are freque… Show more
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