Cystatin C and Its Temporal Change May Predict Development and Recovery of Cardio-renal Syndrome Type 1 in Acute Heart Failure

Açıkgöz, Eser; Açi̇kgöz, Sadık Kadri; Özilhan, Murat Oğuz; Candemir, Mustafa; Gökalp, Gökhan; Karaaslan, Özge Çakmak; Nurkoç, Serdar Gökhan; Kocak, Ajar; Gülbahar, Özlem; Özdemir, Hüseyin Murat

doi:10.32596/ejcm.galenos.2022.2022-01-01

Cited by 1 publication

(3 citation statements)

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“…We retrieved a total of 35 414 articles, and after excluding duplicates, we obtained 25 525 articles. Following a review of the titles and abstracts, 410 articles were selected for full‐text reading, with 37 studies, 7–43 eventually being included for the final meta‐analysis. Figure shows the process of screening the literature and results.…”

Section: Resultsmentioning

confidence: 99%

“…We retrieved a total of 35 414 articles, and after excluding duplicates, we obtained 25 525 articles. Following a review of the titles and abstracts, 410 articles were selected for full‐text reading, with 37 studies, 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 eventually being included for the final meta‐analysis. Figure 1 shows the process of screening the literature and results.…”

Section: Resultsmentioning

confidence: 99%

“…Hence, using Stata 16.0 software, we integrated a total of 15 risk factors. The risk factors were categorized as follows: (1) as per general factors: age, 14 , 17 , 29 , 43 gender (male) 14 , 29 , 30 ; (2) based on disease factors: diabetes (yes vs. no), 8 , 16 , 29 , 30 hypertension (yes vs. no), 16 , 29 history of chronic kidney disease (yes vs. no), 14 , 30 , 36 CHF systolic (systolic vs. diastolic) 30 , 33 ; (3) based on objective indicator factors: LVEF, 12 , 36 N‐terminal pro‐B‐type natriuretic peptide, 14 , 16 , 29 creatinine, 12 , 24 , 29 , 33 creatinine >1.0 mg/day (yes vs. no), 19 , 30 , 35 index estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m 2 (yes vs. no), 8 , 32 index eGFR, 16 , 32 blood urea nitrogen 19 , 35 ; (4) based on therapeutic factors: intravenous dobutamine (yes vs. no) 19 , 35 ; (5) protective factors: serum albumin. 14 , 24 , 29 , 32 The meta‐analysis revealed that 10 of the influencing factors were predictor factors ( P < 0.05).…”

Section: Resultsmentioning

confidence: 99%

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Incidence, mortality, and predictors of acute kidney injury in patients with heart failure: a systematic review

Ru,

Lv,

2023

ESC Heart Failure

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Acute kidney injury (AKI) is common in patients with heart failure (HF), but studies have been inconsistent about the incidence of AKI in patients with HF. We conducted a meta‐analysis to examine the incidence of AKI and its impact on mortality in patients with HF. We also looked at inpatient variables that could predict the development of AKI to identify potential risk factors, so that these can be used as a starting point for intervention and prevention in this group. The Embase, Medline, PubMed, Cochrane libraries, and Web of Science databases were used for searching articles from the inception of the database to October 2022. The EndNote software was used for screening. Meta‐analysis was performed using Stata 16.0 software to combine effect sizes. A total of 37 studies were included. Of all the 3 533 583 patients with HF, 774 887 had AKI, with a pooled incidence of 33% [95% confidence interval (CI): 32–35%]. The incidence rate of AKI in acute HF and chronic HF was 36% (95% CI: 31–40%) and 30% (95% CI: 24–35%), respectively. Eleven studies found that AKI patients had higher in‐hospital mortality than non‐AKI patients [risk ratio (RR): 3.65; 95% CI: 3.04–4.39, P < 0.001]. Mortality was assessed in five studies, and it was found that mortality remained high at 1‐year follow‐up after onset of AKI (RR: 1.85, 95% CI: 1.54–2.22, P < 0.001). Fifteen admission variables were included and analysed in 13 studies. The combined results showed that diabetes, hypertension, history of chronic kidney disease, chronic HF systolic, age, N‐terminal pro‐B‐type natriuretic peptide, creatinine > 1.0 mg/dL, index estimated glomerular filtration rate < 60 mL/min/1.73 m2, blood urea nitrogen > 24 mg/dL, intravenous dobutamine, and serum albumin were predictor factors for HF patients with AKI (P < 0.05). In this meta‐analysis, AKI occurred in approximately 33% of HF patients during hospitalization and the risk of dying in the hospital was tripled. Even during 1‐year long‐term follow‐up, the risk of death remained high, and multiple inpatient variables showed that HF patients tended to have AKI. Early intervention and treatment are important to reduce the incidence of AKI and improve the prognosis.

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“…We retrieved a total of 35 414 articles, and after excluding duplicates, we obtained 25 525 articles. Following a review of the titles and abstracts, 410 articles were selected for full‐text reading, with 37 studies, 7–43 eventually being included for the final meta‐analysis. Figure shows the process of screening the literature and results.…”

Section: Resultsmentioning

confidence: 99%

“…We retrieved a total of 35 414 articles, and after excluding duplicates, we obtained 25 525 articles. Following a review of the titles and abstracts, 410 articles were selected for full‐text reading, with 37 studies, 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 eventually being included for the final meta‐analysis. Figure 1 shows the process of screening the literature and results.…”

Section: Resultsmentioning

confidence: 99%