Cystic clear cell acanthoma

Hamaguchi, Taizo; Penneys, Neal S.

doi:10.1111/j.1600-0560.1995.tb01407.x

Cited by 13 publications

(11 citation statements)

References 9 publications

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“…It appears mainly on the lower leg as a slightly elevated, dome‐shaped, erythematous nodule with thin wafer‐like scales providing a peripheral collarette. Variant forms of CCA have been reported, including giant (3, 4), multiple (5, 6), cystic (7), and pigmented (8) cases, and those associated with epidermal nevus (9, 10) and melanocytic nevus (11). Polypoid CCA has also been reported by some authors (11–15).…”

Section: Discussionmentioning

confidence: 99%

A Case of Polypoid Clear Cell Acanthoma on the Scrotum

Kawaguchi

Tatewaki

Takeuchi

2004

The Journal of Dermatology

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A red nodule appeared on the left side of the scrotum of a 37-year-old Japanese man and slowly grew for four years. When he first visited us, it was 5 mm in diameter, polypoid shaped, and had a smooth and slightly moist surface. Histologically, acanthosis, parakeratosis, and dilated blood vessels were seen in the upper dermis. In higher magnification, the thick epidermis consisted of tumor cells with slightly enlarged nuclei and pale cytoplasm, and neutrophils were also seen among the tumor cells. The cytoplasm of the tumor cells was stained with periodic-acid-Schiff (PAS), and the positive reaction was digested by diastase. There has been no previous report of polypoid clear cell acanthoma in Japan, and only a few reports from the rest of the world. In addition, clear cell acanthoma arising on the scrotum is particularly unusual.

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Section: Discussionmentioning

confidence: 99%

A Case of Polypoid Clear Cell Acanthoma on the Scrotum

Kawaguchi

Tatewaki

Takeuchi

2004

The Journal of Dermatology

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“…The common locations of CCA include the leg, thigh, back, abdomen and chest 5 . Uncommon locations include the nipple, 6,24 vermilion mucosa of lower lips, 53 hallux/toe, 54 palm, 49 genitalia, 21 scrotum, 37 suprapubic, 47 umbilicus 50 and scalp 35…”

Section: Clinical Presentation and Variantsmentioning

confidence: 99%

“…There is only one report of this variant in the English literature. Hamaguchi et al 47 reported a case of cystic CCA in the suprapubic area of a middle-aged man. On histopathological examination, the lesion was diagnosed as a typical CCA with cystic hair shafts, which was surrounded by a condensed connective-tissue sheath.…”

Section: Cystic Clear Cell Acanthomamentioning

confidence: 99%

Clear cell acanthoma

Tempark

Shwayder

2012

Clinical and Experimental Dermatology

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SummaryClear cell acanthoma (CCA), is an asymptomatic benign lesion of unknown origin and aetiology, which typically presents as a red to brown, dome-shaped papule on the leg. We discuss the case of a patient with an irregular plaque of hypopigmented papules whose diagnosis of CCA was only made by biopsy, and review the characteristic presentation, uncommon variants, locations and associated conditions of this lesion. The diagnosis is based on histopathology and ⁄ or immunohistochemistry, but the variable clinical presentation may make diagnosis difficult. The differential diagnosis includes skin tumours and inflammatory and pigmentary dermatoses. The lesions do not regress spontaneously, and excisional removal is the preferred treatment.

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“…Multiple CCA are uncommon and predominantly located on legs, but they may appear on head, torso, and upper limbs 3 . Other unusual clinical types include giant, polypoid, pigmented, and cystic CCA 1,2,4,5 . CCA has developed on pre‐existing lesions (e.g.…”

Section: Unusual Locations and Variants Of Clear Cell Acanthoma (Cca)mentioning

confidence: 99%