Cystic peripheral cholangiocarcinoma: sonography and CT

Lee, S. K.; Choi, Byung Ihn; Cho, J. M.; Han, Joon Koo; Kim, Y. I.; Han, Man Chung

doi:10.1007/bf00201520

Cited by 14 publications

(7 citation statements)

References 5 publications

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“…Various patterns on imaging have been reported previously in cases of mucinous CC, [1][2][3]9,10 although the predominant histological features were similar in each. The differences in gross appearance might be due to the location of tumour origin and the mode of spread.…”

Section: Discussionmentioning

confidence: 72%

C ASE R EPORT: Mucinous cholangiocarcinoma featuring a multicystic appearance and periportal collar in imaging

Mizukami

Ohta

Arisato

et al. 1999

J of Gastro and Hepatol

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A case of mucinous cholangiocarcinoma (CC), a rare histological type of CC, featuring unusual images is reported. The patient was hospitalized because of acute development of jaundice and fever. Computed tomography demonstrated multiple cystic lesions in the liver and a band-like low density area parallel to the intrahepatic portal vein, a so-called 'periportal collar'. Endoscopic cholangiography revealed a stricture of the hepatic duct with slight upstream dilatation. Cytology of the bile juice and fine-needle aspiration of the cystic lesion in the liver disclosed mucinous carcinoma. The patient died of multiorgan failure 3 weeks after admission. The autopsied liver showed that multiple mucus lakes were lined with adenocarcinoma cells and signet ring cells were floating in the mucus lakes. The cancer cells had spread along the portal tract and invaded into the hepatic parenchyma.

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Section: Discussionmentioning

confidence: 72%

C ASE R EPORT: Mucinous cholangiocarcinoma featuring a multicystic appearance and periportal collar in imaging

Mizukami

Ohta

Arisato

et al. 1999

J of Gastro and Hepatol

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“…These types of cystic lesions have been reported to be signs of cystic degeneration of the tumor. 12,13 Thus, as they are derived from the tumor itself, drainage was considered to have seeded the tumor along the biliary tract and portal vein in our patient. As a result, drainage of the cystic lesion induced acute exacerbation of the tumor, promoting intrahepatic metastasis, and invasion of the hepatic hilum.…”

Section: Discussionmentioning

confidence: 93%

“…12,13 In the other type of cholangiocarcinoma, two cases of major duct cholangiocarcinoma were reported to have multiple simple biliary cysts. 8 In our patient, the cystic formation led to an incorrect diagnosis, and preoperative drainage of the cyst changed the CT image, accelerating tumor progression due to intrahepatic tumor seeding, and making the patient's clinical course more complicated.…”

Section: And Onmentioning

confidence: 99%

Rapid Progression of Intrahepatic Cholangiocarcinoma After Drainage of Large Cystic Lesions: Report of a Case

et al. 2000

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We report herein a case of cholangiocarcinoma with large cystic lesions. Computed tomography (CT) demonstrated large cysts in segment IV and the paracaval portion of the caudate lobe, and a solid tumor in the anterior segment of the right lobe of the liver which was contiguous to the cyst in the paracaval portion of the caudate lobe. The large cysts were diagnostically misleading and a liver abscess was suspected. Thus, percutaneous transhepatic drainage of the cyst was performed. The fluid in the cyst was negative bacteriologically, but malignant cells were detected. A CT scan done 2 weeks after drainage of the cyst showed progression of the solid tumor with intrahepatic metastasis and replacement of the cystic lesions by the solid tumor. Following percutaneous transhepatic portal embolization, a right hepatic trisegmentectomy with caudate lobectomy was performed. Pathological examination confirmed cholangiocellular carcinoma. These results indicate that drainage of the cystic lesion induced the tumor progression in the liver. Therefore, the possibility of cholangiocarcinoma with a large cystic lesion should be borne in mind when considering the differential diagnosis of a cystic lesion in the liver, and appropriate surgical therapy should be carefully selected.

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“…During the observation period, examination revealed a tumor that grew at the location of the cysts. To the best of our knowledge, only a few cases of cholangiocarcinoma closely related to liver cysts were reported in English literature (5)(6)(7)(8).…”

Section: Introductionmentioning

confidence: 99%

Malignant Transformation of Liver Cysts Into Cholangiocarcinoma During Follow-up: Potential Dangers of Liver Cysts

Liu

et al. 2021

Preprint

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Background: The liver cyst is a common disease in hepatobiliary surgery. Most patients have no apparent symptoms and are usually diagnosed accidentally during imaging examinations. The vast majority of patients with liver cysts follow a benign course, with very few serious complications and rare reports of malignant changes. Case Presentation: We present two cases of liver cysts that evolved into intrahepatic tumors during the follow-up process. The first patient had undergone a fenestration and drainage operation for the liver cyst, and the cancer was found at the cyst’s position in the third year after the procedure. Microscopically, bile duct cells formed the cyst wall. Tumor cells can be seen on the cyst wall and its surroundings to form adenoid structures of different sizes, shapes, and irregular arrangements, some of which are arranged in clusters. The second patient was regularly rechecked after discovering liver cysts, and a new mass appeared very close to the cyst. The clinical manifestations and laboratory examinations of the two patients lacked specificity, the preoperative diagnosis was unclear, and the postoperative pathology confirmed cholangiocarcinoma.Conclusions: Our cases indicate that liver cysts may lead to the occurrence of malignant intrahepatic cholangiocarcinoma. Therefore, follow-up of particular liver cysts is necessary, and the differential diagnosis of the intrahepatic cystic tumors needs to include cholangiocarcinoma.

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Cystic peripheral cholangiocarcinoma: sonography and CT

Cited by 14 publications

References 5 publications

C ASE R EPORT: Mucinous cholangiocarcinoma featuring a multicystic appearance and periportal collar in imaging

C ASE R EPORT: Mucinous cholangiocarcinoma featuring a multicystic appearance and periportal collar in imaging

Rapid Progression of Intrahepatic Cholangiocarcinoma After Drainage of Large Cystic Lesions: Report of a Case

Malignant Transformation of Liver Cysts Into Cholangiocarcinoma During Follow-up: Potential Dangers of Liver Cysts

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