Cystosarcoma phyllodes: Our institutional experience

Joshi, Sanjeev Chandra; Sharma, Daya Nand; Bahadur, Anil Kumar; Maurya, Rajesh Kumar; Kumar, Sunil; Khurana, Nita

doi:10.1046/j.1440-1673.2003.01215.x

Cited by 28 publications

(17 citation statements)

References 19 publications

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“…The role of adjuvant radiotherapy and chemotherapy remains uncertain, but consideration can be given for their use in cases of malignant phyllodes tumours [2], [32], [33].…”

Section: Discussionmentioning

confidence: 99%

The largest and neglected giant phyllodes tumor of the breast—A case report and literature review

Islam

Shah

Harnarayan

et al. 2016

International Journal of Surgery Case Reports

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HighlightsThe Finding of a giant phyllodes tumor is very rare.The diagnosis should be entertained in all patients presenting with progressive enlargement of breast lump.Emphasis should be given in early diagnosis and treatment to decrease morbidity and mortality.Core needle biopsy is key method of preoperative diagnosis of phyllodes tumour Emphasis should be given on proper health education on breast cancer and its management.Patient needs to be well educated about the negative consequences of alternative or delayed treatment.

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“…The role of adjuvant radiotherapy and chemotherapy remains uncertain, but consideration can be given for their use in cases of malignant phyllodes tumours [2], [32], [33].…”

Section: Discussionmentioning

confidence: 99%

The largest and neglected giant phyllodes tumor of the breast—A case report and literature review

Islam

Shah

Harnarayan

et al. 2016

International Journal of Surgery Case Reports

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“…26–33 Several studies describe the successful use of adjuvant radiotherapy in small numbers of patients after margin-positive mastectomies. 11,34–36 …”

Section: Discussionmentioning

confidence: 99%

“…Given an approximately 10% incidence of chest wall recurrence after mastectomy, evidence that adjuvant radiation can prevent local recurrence after margin positive mastectomies, and the data we have now described regarding the effectiveness of adjuvant radiation after margin-negative breast-conserving resections, it seems reasonable to consider adjuvant postmastectomy radiation in these patients. 6,11,34–36 …”

Section: Discussionmentioning

confidence: 99%

A Prospective, Multi-Institutional Study of Adjuvant Radiotherapy After Resection of Malignant Phyllodes Tumors

et al. 2009

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Background Malignant phyllodes tumors of the breast are unusual neoplasms, with an incidence of approximately 500 cases annually in the United States. Published local recurrence rates after margin-negative breast-conserving resections of borderline malignant and malignant phyllodes tumors are unacceptably high, at 24 and 20%, respectively. It is uncertain whether radiotherapy after resection of phyllodes tumors is beneficial. Methods We prospectively enrolled patients who were treated with a margin-negative breast-conserving resection of borderline malignant or malignant phyllodes tumors to adjuvant radiotherapy. The primary endpoint was local recurrence. Results Forty-six women were treated at 30 different institutions. The mean patient age was 49 years (range, 18–76 years). Thirty patients (65%) had malignant phyllodes tumors; the rest were borderline malignant. The mean tumor diameter was 3.7 cm (range, .8–11 cm). Eighteen patients had a negative margin on the first excision. The median size of the negative margin was .35 cm (range, <.1–2 cm). Twenty-eight patients underwent a re-excision because of positive margins in the initial resection. Two patients died of metastatic phyllodes tumor. During a median follow-up of 56 months (range, 12–129 months), none of the 46 patients developed a local recurrence (local recurrence rate, 0%; 95% confidence interval, 0–8). Conclusions Margin-negative resection combined with adjuvant radiotherapy is very effective therapy for local control of borderline and malignant phyllodes tumors. The local recurrence rate with adjuvant radiotherapy was significantly less than that observed in reported patients treated with margin-negative resection alone.

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“…[13,14] Although Confavreux et al failed to demonstrate any improvement of the overall survival in cases in which adjuvant radiation therapy was associated, some other authors sustain the benefit of this oncologic adjuvant treatment. [15,16] The benefits of complete R0 resection at the time of surgery has been widely demonstrated in clinical studies and remains one of the most important factors which increases the overall survival. [16][17][18][19] In Popescu's study conducted between 1960 and 1989 in Fundeni Clinical Hospital, 19 cases with benign (15 cases) and malignant (4 cases) PT were included.…”

Section: Discussion Discussionmentioning

confidence: 99%

Total mastectomy for phyllodes malignant tumor in an elderly patient

Bacalbaşa¹,

Bălescu²,

Brasoveanu³

2014

JTMR

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Phyllodes tumors are rare neoplasms accounting for less than 1% of all breast malignancies. Under this generic name more histopathological subgroups are included. Malignant phillodes tumors represent less than a quart of all phillodes tumors and are associated with a more aggressive biological behaviour with a higher tendency to both local and distant metastases. One of the most important prognostic factors in order to increase the overall ssurvival in these cases remains a wide excision of the primary tumor. We present a case of a 69 years old patient diagnosed with a large tumor deforming the left breast in whom the results of the punction-biopsy revealed a Phylodes malignant tumor. A total mastectomy was performed.

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Cystosarcoma phyllodes: Our institutional experience

Cited by 28 publications

References 19 publications

The largest and neglected giant phyllodes tumor of the breast—A case report and literature review

The largest and neglected giant phyllodes tumor of the breast—A case report and literature review

A Prospective, Multi-Institutional Study of Adjuvant Radiotherapy After Resection of Malignant Phyllodes Tumors

Total mastectomy for phyllodes malignant tumor in an elderly patient

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