2014
DOI: 10.1039/c4ra01047g
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Cyto and genotoxicities of graphene oxide and reduced graphene oxide sheets on spermatozoa

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Cited by 122 publications
(83 citation statements)
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“…[28,[36][37][38][39][40] For example, recent studies have demonstrated the size-and concentration-dependent cyto-and even genotoxicity of graphene-based materials on human mesenchymal stem cells and spermatozoa. [43][44][45] Although there have been several investigations on the cytotoxicity of graphene-based materials on various cell lines, [30,[46][47][48][49][50] there are only few reports on the biocompatibility of AuNPsrGO composites. [51][52][53] For the assessment of the biocompatibility of AuNPs-rGO, its cytotoxicity to HeLa cells was evaluated in vitro.…”
Section: Cytotoxicity Studiesmentioning
confidence: 99%
“…[28,[36][37][38][39][40] For example, recent studies have demonstrated the size-and concentration-dependent cyto-and even genotoxicity of graphene-based materials on human mesenchymal stem cells and spermatozoa. [43][44][45] Although there have been several investigations on the cytotoxicity of graphene-based materials on various cell lines, [30,[46][47][48][49][50] there are only few reports on the biocompatibility of AuNPsrGO composites. [51][52][53] For the assessment of the biocompatibility of AuNPs-rGO, its cytotoxicity to HeLa cells was evaluated in vitro.…”
Section: Cytotoxicity Studiesmentioning
confidence: 99%
“…Recently, it was found that green tea polyphenol-functionalized rGO sheets can also decrease the reactive oxygen species (ROS) generated in cell culture media, while hydrazine-rGO sheets induce more ROS generation [39].…”
Section: Introductionmentioning
confidence: 99%
“…Hence, graphene has promisingly been used in a broad range of nanotechnology-based bio-applications including DNA/RNA extractions [6,7], extremely sensitive biosensing [8], disease diagnosis [9,10], drug delivery [11,12], anti-bacterial [13][14][15], parasitical [16] and viral [17] intentions, effective cancer cell targeting, imaging and therapy [18][19][20][21][22][23], and altering the genetic characteristics of spermatozoa [24] and stem cells [25]. Recently, graphene layers have successfully been utilized in upcoming stem cell-based tissue engineering as 2D-scaffolds [26][27][28].…”
Section: Introductionmentioning
confidence: 99%