Cytodiagnosis of lesions presenting as salivary gland swellings: A report of seven cases

Chan, May K.M.; McGuire, Lloyd

doi:10.1002/dc.2840080503

Cited by 49 publications

(45 citation statements)

References 11 publications

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“…[10] Kimura hastalığında hücresel a tipi hemen hiçbir zaman görülmemiştir. [11,12] Eozinofilik anjiyolenfoid hiperplazi ise daha çok 20-50 yaş aralığında özellikle kadınlarda görülen deri içi lezyonlarla seyreden etyolojisi tam olarak aydınlatılamamış ancak lezyonlarda östrojen reseptörü olması nedeniyle östrojene bağlı bir tümör olduğu düşünülen kronik enflamatuvar bir vasküler hadisedir. [13] Nodüler lezyonlar 2-3 cm'den daha küçük boyutta, pulsatil erimatöz, kaşıntılı ve kırılgan özeliktedir.…”

Section: Discussionunclassified

Atypical presentation in Kimura’s disease

Bayır

Karagöz²,

Tatar³

et al. 2015

Kulak Burun Bogaz Ihtis Derg

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Section: Discussionunclassified

Atypical presentation in Kimura’s disease

Bayır

Karagöz²,

Tatar³

et al. 2015

Kulak Burun Bogaz Ihtis Derg

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“…There are several reports in the literature describing its cytologic features and addressing the main differential diagnosis and its diagnostic pitfalls. [3][4][5][6][7][8][9][10][11][12][13][14] However, a review of the literature showed that out of the 34 reported cases, a correct cytologic diagnosis was made in only 12 cases, one of these on repeat FNAB. Most of the cases were reported as carcinoma, mainly squamous cell carcinoma, or suggestive of carcinoma (Table 1).…”

Section: Discussionmentioning

confidence: 99%

“…It was described by Woyke et al as eosinophilic clumps, 4 and by Chan and McGuire as birefringent keratin material. 8 Unger et al recognized these masses as compact sheets of ghost cells. 6 Because of their prominent optical characteristic, Wong et al found them to be the most helpful feature in alerting the pathologist to look for ghost cells, leading to the diagnosis of pilomatrixoma.…”

Section: Discussionmentioning

confidence: 99%

Pilomatrixoma: Fine-Needle Aspiration Cytology a Report of Three Cases

Tulbah

Akhtar

1997

Ann Saudi Med

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A Tulbah, M Akhtar, Pilomatrixoma: Fine-Needle Aspiration Cytology a Report of Three Cases. 1997; 17(1): 88-91 Pilomatrixoma, or calcifying epithelioma of Malherbe, is a benign tumor of skin appendages with presumed differentiation towards hair cortical cells. The term pilomatrixoma is preferred to the former name of "calcifying epithelioma of Malherbe," which may give the unwary clinician a false impression that the lesion is malignant. It manifests clinically as a firm, deep-seated nodule, located mainly on the head, neck and upper extremities. It may arise in persons of any age, but about 40% arise in children younger than 10 years and 60% in the second decade of life. Histologically, it is composed of solid nests of small basaloid cells. The key feature is the presence of abrupt keratinization of these cells, leading to the formation of ghost or shadow cells. Foreign body reaction, calcification and ossification are common secondary events.1,2 Although several studies describing the cytologic features of pilomatrixoma have been reported in the literature, this lesion continues to cause difficulty in diagnosis on a cytologic basis. 13,14 In this paper, we present the cytologic findings in three cases of pilomatrixoma in which fineneedle aspiration biopsy (FNAB) was performed. Definitive diagnosis of pilomatrixoma was rendered in only two of these cases. The cytologic features of pilomatrixoma are discussed with a review of the literature. Material and MethodsThree cases of pilomatrixoma in which FNAB was performed form the basis of this study. Two of these underwent surgical resection following the FNAB, while in the third case no surgery was performed, since FNAB diagnosis was definitive. Fine-needle biopsy was done using a 25 x 1 inch and a 23 x 1 inch gauge needle, without aspiration. The material was smeared on unfrosted slides and the smears were air-dried and stained by Diff-Quik method. Case Reports Case 1A two-year-old female presented with a two-month history of a mass on the back of the neck, which gradually increased in size. The lesion was 2 x 2 cm, hard, mobile, and nontender, and located in the occipital area. The overlying skin was normal. FNAB was performed, followed by surgical resection. Case 2A 12-year-old female presented with a two-and-a-half-month history of a mass in the preauricular area on the right side of the face. It was slightly tender, firm and mobile. The skin overlying it was tethered and discolored. FNAB was performed, followed by surgical resection. Case 3An 11-year-old female presented with a 0.5-cm firm, mobile subcutaneous nodule on the shoulder. FNAB was performed. Results Cytologic FindingsThe smears in all three cases were moderately cellular (Figure 1). The main cell population was basaloid. These were present as sheets of various sizes, as well as isolated cells. The cells had a high nuclear cytoplasmic ratio and scanty basophilic cytoplasm. Their nuclei were round to oval with fairly regular outline and prominent nucleoli

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“…In the head and neck region they occur most commonly in the internal acoustic meatus, with most of them were benign schwannomas, with only one was reported as malignant schwannoma 4 In our patient, FNAC was not helpful for diagnosis, and we believe FNAC guided by ultrasound is needed for a more informative cytology, as has been reported with other cases 7,8 . The pattern on and MR images shows more of myxomatous tissue which raise a possibility of it not being a simple benign tumour 8,9 Treatment should be confined to complete surgical excision, and wide excision is not recommended. Longterm follow-up of the schwannomas shows few schwannomas recur after complete excision 10 .…”

Section: Case Summarymentioning

confidence: 99%

A Rare Schwannoma Of The Submandibular Gland: A Case Report

Nasir

Susibalan

Soleh

et al. 2018

Int. J. Hum. Health Sci.

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Abstract:Schwannomas are benign tumors arising from Schwann cells of the sheaths of peripheral nerves. Although vagus nerve and sympathetic chain composed of sympathetic fibers is one of the most common sites of schwannomas in extracranial head and neck region, many cases of origin unknown schwannomas were reported. We report an unusual rare case of a submandibular gland schwannoma in a 67-year-old lady, who was successfully treated by surgical excision with no cranial nerve deficits and complete resolution of the symptoms postoperatively. In this report, we establish a rare findings of schwannoma of the submandibular gland and to the best of our knowledge, this is the first case-report of schwannoma of submandibular gland reported from a tertiary hospital in the east coast of Malaysia.

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Cytodiagnosis of lesions presenting as salivary gland swellings: A report of seven cases

Cited by 49 publications

References 11 publications

Atypical presentation in Kimura’s disease

Atypical presentation in Kimura’s disease

Pilomatrixoma: Fine-Needle Aspiration Cytology a Report of Three Cases

A Rare Schwannoma Of The Submandibular Gland: A Case Report

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