Cytogenetics, Distribution and Phenotypic Effects of a Translocation in Swedish Cattle

Gustavsson, I.

doi:10.1111/j.1601-5223.1969.tb02259.x

Cited by 157 publications

(32 citation statements)

References 99 publications

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“…Robertsonian translocations have been documented, such as rob (15;25), rob(1;29), rob(2;28), rob(15;25), rob(7;21), rob(4;20), rob(16;18), rob(16;20), rob(4;10), and so on. Of the Robertsonian translocations, rob(1;29) and rob(2;28) were the most common, which were considered as ancient origin with reduced fertility (subfertility) in the heterozygous carriers (Gustavsson, 1969;Blazak and Eldridge, 1977;Popescu, 1990;Rubes et al, 1999;Vadhanakul et al, 2004).…”

Section: Introductionmentioning

confidence: 99%

Karyotype analysis of mithun (Bos frontalis) and mithun bull x Brahman cow hybrids

Qu¹,

He²,

Nie³

et al. 2012

Genet. Mol. Res.

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ABSTRACT. We examined the cytogenetics of mithun (Bos frontalis), a domesticated version of the Asian gaur, and hybrids (F 1 generation) produced by artificial insemination of Brahman cows (Bos indicus) with mithun semen. Reproductive potential was also examined in the F 1 generation and a backcrossed heifer for utilization of heterosis. Metaphase chromosome spreads were examined by conventional staining and fluorescence in situ hybridization hybridized with the entire chromosome 1 of mithun as a specific probe. Chromosome 1 of mithun was found to be equivalent to Bos taurus chromosomes 2 and 28. The karyotype of the female mithun (N = 4) comprised 58 chromosomes, including 54 acrocentric and four large submetacentric chromosomes, without the four acrocentric chromosomes found in the domesticated species B. indicus. However, one of the four female mithuns with a normal mithun phenotype had an abnormal karyotype (2n = 59), indicating introgression from B. taurus or B. indicus. The F 1 karyotypes (N = 6, 3♂3♀) of the mithun bull × Brahman cow cross had 2n = 59, intermediate between their parents; they were consistent heterozygous carriers with a centric fusion involving rob(2;28), as expected. Two pronounced red signals were seen in the mithun karyotypes, three red signals in the mithun × Brahman hybrids, and four red signals in the Brahman cattle, in good agreement with centric fusion of bovine rob(2;28). The female backcross hybrid (N = 1) with 2n = 59 had a similar chromosome configuration to the F 1 karyotypes and had rob(2;28). Such female backcross hybrids normally reproduce; however, the F 1 bulls (N = 3)had not yet generated normal sperm at 24 months.

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Section: Introductionmentioning

confidence: 99%

Karyotype analysis of mithun (Bos frontalis) and mithun bull x Brahman cow hybrids

Qu¹,

He²,

Nie³

et al. 2012

Genet. Mol. Res.

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“…There was also a regular formation of twenty-four bivalents in diplotene, diakinesis and first metaphase. The rare occurrence of tetraploid spermatocytes, dissociated sex bivalents and small autosomal bivalents in the first meiotic metaphase are features also observed in other mammals (ELIAS-SON et al 1968;GUSTAVSSON 1969). The unsystematical variation of chromosome numbers observed in the secondary spermatocytes are probably ascribable to the preparation technique used.…”

Section: Meiotic Chromosomesmentioning

confidence: 69%

Mitotic and meiotic chromosomes of the variable hare (Lepus timidus L.), the common hare (Lepus europaeus Pall.) and their hybrids

Gustavsson¹

2009

Hereditas

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Mitotic and meiotic chromosome studies in the variable hare (Lepus timidus L.), the common hare (Lepus europaeus PALL.) and their hybrids have shown a diploid chromosome number of 48. No differences in chromosome structure could bc established between the two species. There was a normal meiotic behaviour of the chromosomes in the male hybrids with the formation of secondary spermatocytes with a normal haploid chromosome complement. The hybrids appeared to have a normal fertility and the reproductive barrier existing between the two species was apparently not built up by sterility factors.

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“…The BGA1 chromosome is similar to the rob(1;29) of cattle, the most famous and widely spread chromosome abnormality in this species (Gustavsson 1969;Popescu and Pech, 1991;Di Meo et al, 2000). A combination of banding and FISH-mapping techniques with specific molecular markers mapping proximally to BTA29 and three SAT DNA (SAT I, SAT III and SAT IV) demonstrated that also the rob(1;29) of cattle originated by complex chromosomal rearrangements: a centric fusion translocation is followed by a pericentric inversion or chromosome transposition of a small proximal region of the p-arm (BTA29) to the proximal q-arm (BTA1) of the translocated chromosome (Chaves et al 2003;Di Meo et al 2006;Iannuzzi et al 2009).…”

Section: Resultsmentioning

confidence: 96%

Chromosome evolution of the Malayan gaur (Bos gaurus hubbacki)

et al. 2012

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A GTG-banding comparison between the chromosomes of gaur (Bos gaurus hubbacki, BGA, 2n = 56) and those of domestic cattle (Bos taurus, BTA, 2n = 60) was performed to establish chromosome homoeologies or differences between the two species. The two biarmed chromosomes of gaur (BGA1 and BGA2) were originated by centric fusion translocations between homoeologous cattle chromosomes 1/29 (BGA1) and 2/28 (BGA2). High resolution GTG-banding comparison between BGA1 and BTA1/BTA29 revealed that BGA1q differentiated from BTA1 by a paracentric inversion of a large and proximal chromosome region (BTA1q13-q32). To our knowledge, this is the first case of a bovid biarmed chromosome originated by centric fusion and paracentric inversion during karyotype evolution. The CBG-banding pattern showed clear C-bands in all autosomes, although the two biarmed pairs showed smaller C-bands, especially in BGA2. The results were discussed on the basis of previous results obtained in other bovid species, including the carriers of rob(1;29) of cattle, the most known and widely spread chromosome abnormality in Bos taurus.

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Cytogenetics, Distribution and Phenotypic Effects of a Translocation in Swedish Cattle

Cited by 157 publications

References 99 publications

Karyotype analysis of mithun (Bos frontalis) and mithun bull x Brahman cow hybrids

Karyotype analysis of mithun (Bos frontalis) and mithun bull x Brahman cow hybrids

Mitotic and meiotic chromosomes of the variable hare (Lepus timidus L.), the common hare (Lepus europaeus Pall.) and their hybrids

Chromosome evolution of the Malayan gaur (Bos gaurus hubbacki)

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