Cytologic Criteria of Cystic Papillary Carcinoma of the Thyroid

Needle Tract Sinus Following Aspiration Biopsy of Papillary Thyroid Carcinoma

“…Although clinical and radiologic evidence pointed toward a malignant thyroid neoplasm, repeated FNAs were reported as negative because of a lack of distinctive cytomorphologic features of papillary thyroid carcinoma. 8 Thus intraoperative frozen section was performed to confirm the diagnosis, and a debulking surgery was done in our patient.…”

Diagnostic Difficulties in the Interpretation of Fine Needle Aspirate Samples in Salivary Lesions

“…18,19,34 Along with psammoma bodies, both can show papillary clusters and produce colloid-like material. 21,35 The acinar cells also can resemble Hürthle cells, or the cytoplasmic vacuolizations seen in both conditions, as well as the inconspicuous nucleoli in some variants of acinic cell carcinomas, makes them appear similar. 19,21,34,35 Carotid body tumors can show isolated as well as follicular clusters of various-sized cells as well as giant cells, such as seen in our case, which can be confused with adenocarcinomas, undifferentiated tumors and follicular thyroid cancers.…”

“…21,35 The acinar cells also can resemble Hürthle cells, or the cytoplasmic vacuolizations seen in both conditions, as well as the inconspicuous nucleoli in some variants of acinic cell carcinomas, makes them appear similar. 19,21,34,35 Carotid body tumors can show isolated as well as follicular clusters of various-sized cells as well as giant cells, such as seen in our case, which can be confused with adenocarcinomas, undifferentiated tumors and follicular thyroid cancers. 36 Cytologically, metastatic melanoma is recognized easily by the presence of pigmented, oval to round, uninulceated or binucleated tumor cells with occasional intranuclear inclusions.…”

Papillary thyroid carcinoma with atypical histiocytoid cells on fine‐needle aspiration

“…1 The difficulty in extracting the PTC component from background histiocytes is compounded by the fact that the majority of thyroid FNAs are benign and not uncommonly cystic, 7 so focal atypia in this setting may be dismissed inadvertently. 8 In rare instances, PTC with cystic degeneration is devoid of the typical malignant epithelial cells, and instead is composed of atypical histiocytoid cells mimicking benign histiocytes. 9 Because of the semblance of these two cells and their potential for diagnostic pitfall, we evaluated nonneoplastic histiocytes and neoplastic histiocytoid cells in PTC aspirates, with cystic degeneration to identify distinguishing criteria.…”