2018
DOI: 10.14260/jemds/2018/381
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Cytological Variations and Diagnostic Challenges in Pleomorphic Adenomas

Abstract: BACKGROUNDPleomorphic Adenomas are the most common benign neoplasms of the salivary glands and are a diverse group of lesions. Most common site being major salivary glands, of which parotid gland constitutes 64% -80%. Fine Needle Aspiration Cytology (FNAC) of palpable salivary lesions is accepted as a useful preoperative diagnostic tool worldwide. Cytomorphological and histological diversity encountered in pleomorphic adenomas causes enormous diagnostic difficulty. Objective-The present study was done to evalu… Show more

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Cited by 1 publication
(2 citation statements)
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“…2,26,27 Usually, the distinction is readily made, except in PAs with a significant canalicular pattern (similar to cribriform), which will produce clumps of epithelial cells with balls of stroma, tubule formation, and myxoid stroma, mimicking adenoid cystic carcinoma. 28,29 This feature is found in approximately 5% of PA cases. 30 If the aspirate samples only this area, then the diagnosis may be missed.…”
Section: Discussion/conclusionmentioning
confidence: 99%
See 1 more Smart Citation
“…2,26,27 Usually, the distinction is readily made, except in PAs with a significant canalicular pattern (similar to cribriform), which will produce clumps of epithelial cells with balls of stroma, tubule formation, and myxoid stroma, mimicking adenoid cystic carcinoma. 28,29 This feature is found in approximately 5% of PA cases. 30 If the aspirate samples only this area, then the diagnosis may be missed.…”
Section: Discussion/conclusionmentioning
confidence: 99%
“…PA has metachromatic and myxofibrillary stroma, whereas adenoid cystic carcinoma forms hyaline globules 2,26,27 . Usually, the distinction is readily made, except in PAs with a significant canalicular pattern (similar to cribriform), which will produce clumps of epithelial cells with balls of stroma, tubule formation, and myxoid stroma, mimicking adenoid cystic carcinoma 28,29 . This feature is found in approximately 5% of PA cases 30 .…”
Section: Discussion/conclusionmentioning
confidence: 99%