Cytoskeleton and Cell Motility

Risler, Thomas

doi:10.1007/978-0-387-30440-3_112

Cited by 5 publications

(3 citation statements)

References 278 publications

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“…After indentation and penetration of the cancer cells into adjacent tissues, cancer-cell motility-the ability to move-is thought to play an important role in the colonization of other tissues and the formation of metastases [39][40][41]. Along these lines, two papers of this series investigate the mechanisms of cell motility at the level of the cell lamellipodium.…”

Section: Cytoskeleton and Sub-cellular Processes-force Generation At mentioning

confidence: 99%

“…Nolting and Köster [50] study another aspect of the influence of fluid shear flows, namely, that on the networks of keratin intermediate filaments. Intermediate filaments are part of the cytoskeleton along with microtubules, actin filaments, associated proteins, and molecular motors [41,51,52]. One function of these fibrous proteins is to withstand potentially harmful mechanical influences and to guarantee the integrity of the cell [53,54].…”

Section: Influence Of External Biomechanical Conditions On Mechanosenmentioning

confidence: 99%

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Focus on the physics of cancer

Risler

2015

New J. Phys.

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Despite the spectacular achievements of molecular biology in the second half of the twentieth century and the crucial advances it permitted in cancer research, the fight against cancer has brought some disillusions. It is nowadays more and more apparent that getting a global picture of the very diverse and interlinked aspects of cancer development necessitates, in synergy with these achievements, other perspectives and investigating tools. In this undertaking, multidisciplinary approaches that include quantitative sciences in general and physics in particular play a crucial role. This 'focus on' collection contains 19 articles representative of the diversity and state-of-the-art of the contributions that physics can bring to the field of cancer research.

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Section: Cytoskeleton and Sub-cellular Processes-force Generation At mentioning

confidence: 99%

Section: Influence Of External Biomechanical Conditions On Mechanosenmentioning

confidence: 99%

Focus on the physics of cancer

Risler

2015

New J. Phys.

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“…For example, the cytoskeleton fibrillar network has been regarded as a viscoelastic polar gel. 1 This “ gel-like ” nature has been postulated as essential for important cellular mechanics and functional processes. 2,3 More specifically, cytoskeleton viscoelastic nature 4 is essential to carry out cellular motion or persistence of cellular shape.…”

Section: Introductionmentioning

confidence: 99%