D-dimer: issues of laboratory diagnostics

Abstract

D-dimer is a protein fragment, resulting from the breakdown of fibrin during fibrinolysis. D-dimer is considered to be a fairly informative indicator of thrombus formation, since the mechanism of its production starts simultaneously with the process of thrombus formation. A D-dimer test allows evaluating the combination of 2 factors at once: coagulation and fibrinolysis. The marker makes it possible to timely detect their imbalance in case of diseases of the circulatory system (varicose veins, thrombophilia, pulmonary embolism).