DABCO-based ionic liquids: green and recyclable catalysts for the synthesis of barbituric and thiobarbituric acid derivatives in aqueous media

Abstract

A new and straightforward method for the synthesis of 5-arylidine barbituric and thiobarbituric acids through a reaction between barbituric acid and its thio-analogue with aldehydes using [DABCO](SO3H)2(HSO4)2) as an efficient catalyst has been reported.

Introduction of a New Magnetic Nanocatalyst as an Organic‐inorganic Hybrid Framework for the Synthesis of Pyrano[2,3‐d]pyrimidinone(thione)s and Pyrido[2,3‐d]pyrimidines

“…It has been more than two decades that various catalysts have been designed and introduced for the chemical reactions by our research group that each one at least has a distinguished advantage in comparison with other introduced ones . Among them, nano‐catalysts and nano‐magnetic catalysts are a unique field for our research group .…”

Nano‐Zn[2‐boromophenylsalicylaldiminemethylpyranopyrazole]Cl2 as a novel nanostructured Schiff base complex and catalyst for the synthesis of pyrano[2,3‐d]pyrimidinedione derivatives

“…Additionally, some of them can be used as antimalarial, antifungal, analgesic and antibiotic compounds. Various procedures have been introduced for the synthesis of pyrano[2,3‐ d ]pyrimidinedione derivatives in the presence of catalysts such as Zn[ l ‐proline] 2 , ZnO nanopowders, dibutylamine, potassium fluoride, KAl(SO 4 ) 2 ⋅12H 2 O, l ‐proline, Fe 3 O 4 @SiO 2 @(CH 2 ) 3 ‐Urea‐SO 3 H, [DABCO](HSO 3 ) 2 (HSO 4 ) 2 , sulfonic acid nanoporous silica, DABCO, triethylamine, boric acid and nanotitania sulfuric acid . It is noteworthy that some of them have some disadvantages including harsh reaction conditions, low yields and long reaction times.…”

Butane‐1‐sulfonic acid immobilized on magnetic Fe3O4@SiO2 nanoparticles: A novel and heterogeneous catalyst for the one‐pot synthesis of barbituric acid and pyrano[2,3‐d] pyrimidine derivatives in aqueous media

“…[14] Arylidene barbituric acids, as important heterocyclic compounds, can be obtained via the Knoevenagel condensation reaction between barbituric acid and its derivatives with aldehydes or ketones that do not contain α-hydrogen. For this purpose, a variety of catalysts and reagents have been used to facilitate this reaction including CuO nanoparticles, [15] BiCl 3 , [16] [DABCO] (SO 3 H) 2 Cl 2 , [17] Ce 1 Mg x Zr 1 − x O 2 , [18] ZnO, [19] CoFe 2 O 4 , [20] SiO 2 ⋅12WO 3 ⋅24H 2 O, [21] NH 2 SO 3 H [22] and K 2 NiP 2 O 7 . [23] The various biological properties of pyrano[2,3-d] pyrimidine derivatives [24][25][26] cause wide interest in the preparation of these compounds.…”