Dairy consumption and 10-y total and cardiovascular mortality: a prospective cohort study in the Netherlands

Goldbohm, R. Alexandra; Chorus, A.M.J.; Garre, Francisca Galindo; Schouten, Leo J.; Brandt, Piet A. van den

doi:10.3945/ajcn.110.000430

Cited by 154 publications

(177 citation statements)

References 35 publications

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“…Table 1 shows the characteristics of the 18 prospective cohort studies11, 15, 16, 17, 19, 20, 21, 22, 23, 24, 25, 28, 29, 30, 31, 32, 33 including 1 case‐cohort study,29 which comprised 762 414 participants and 29 943 stroke events. Two studies presented sex‐specific results,19, 29 2 comprised only women,17, 28 and 3 only men 20, 30, 32.…”

Section: Resultsmentioning

confidence: 99%

“…Two studies presented sex‐specific results,19, 29 2 comprised only women,17, 28 and 3 only men 20, 30, 32. Eight studies were from Europe,15, 16, 20, 21, 22, 29, 30, 32 5 were from east Asia (China and Japan),11, 19, 24, 31 3 were from the United States, 17, 23, 28 and 1 was from Australia 33.…”

Section: Resultsmentioning

confidence: 99%

“…The sample size of the studies ranged from 2061 to 223 170 and the duration of follow‐up from 8 to 26 years. Six studies reported fatal stroke,11, 19, 29, 30, 33 10 total stroke,16, 17, 20, 22, 23, 24, 25, 28, 32 and 1 both outcomes 15. All studies adjusted for age, sex, and smoking.…”

Section: Resultsmentioning

confidence: 99%

“…For the Nurses’ Health Study we used 2 articles: 1 on low‐fat and high‐fat dairy23 and 1 on other types of dairy 28. One article provided results for 2 studies (Nurses’ Health Study and the Health Professionals Follow up Study)23 and 2 presented results for men and women separately,19, 29 resulting in 18 studies (see flow chart in Figure 1). 11, 14, 15, 16, 17, 19, 20, 21, 22, 23, 24, 25, 28, 29, 30, 31, 32, 33 …”

Section: Methodsmentioning

confidence: 99%

“…For 4 or more studies, linearity of associations was investigated using spline analysis and dose–response meta‐regression (Generalized Least‐Square Trend). Three studies could not be used for nonlinear analyses, because they only provided linear results 16, 17, 29…”

Section: Methodsmentioning

confidence: 99%

See 4 more Smart Citations

Dairy Consumption and Risk of Stroke: A Systematic Review and Updated Dose–Response Meta‐Analysis of Prospective Cohort Studies

Goede

Soedamah‐Muthu

Pan

et al. 2016

JAHA

114

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BackgroundA higher milk consumption may be associated with a lower stroke risk. We conducted a comprehensive systematic review and dose–response meta‐analysis of milk and other dairy products in relation to stroke risk.Methods and ResultsThrough a systematic literature search, prospective cohort studies of dairy foods and incident stroke in stroke‐free adults were identified. Random‐effects meta‐analyses with summarized dose–response data were performed, taking into account sources of heterogeneity, and spline models were used to systematically investigate nonlinearity of the associations. We included 18 studies with 8 to 26 years of follow‐up that included 762 414 individuals and 29 943 stroke events. An increment of 200 g of daily milk intake was associated with a 7% lower risk of stroke (relative risk 0.93; 95% CI 0.88–0.98; P=0.004; I2=86%). Relative risks were 0.82 (95% CI 0.75–0.90) in East Asian and 0.98 (95% CI 0.95–1.01) in Western countries (median intakes 38 and 266 g/day, respectively) with less but still considerable heterogeneity within the continents. Cheese intake was marginally inversely associated with stroke risk (relative risk 0.97; 95% CI 0.94–1.01 per 40 g/day). Risk reductions were maximal around 125 g/day for milk and from 25 g/day onwards for cheese. Based on a limited number of studies, high‐fat milk was directly associated with stroke risk. No associations were found for yogurt, butter, or total dairy.ConclusionsMilk and cheese consumption were inversely associated with stroke risk. Results should be placed in the context of the observed heterogeneity. Future epidemiological studies should provide more details about dairy types, including fat content. In addition, the role of dairy in Asian populations deserves further attention.

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