Database of processing techniques and processing factors compatible with the EFSA food classification and description system FoodEx2 related to pesticide residues Objective 2: Linking the processing techniques investigated in regulatory studies with the EFSA food classification and description system, FoodEx2

Donkersgoed, Gerda van; Boogaard, Coline van den; Graven, Coen; Koopman, Nynke; Mahieu, Karin; Velde-Koerts, Trijntje van der; Herrmann, Michael; Kittelmann, Arno; Schledorn, Maria von; Scholz, Rebekka; Anagnostopoulos, Chris; Bempelou, Eleftheria; Michalski, Britta

doi:10.2903/sp.efsa.2018.en-1509

Cited by 9 publications

(6 citation statements)

References 4 publications

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“…The entries are restricted to those matrices representing either an end-product used as food or feed or an important intermediate product, because only for those products processing factors are required. These three classes of relevant matrices were highlighted (coloured) in the processing flowcharts provided as an outcome of the first objective of the project (Scholz, 2018) and were selected for FoodEx 2 coding in the context of the second objective of the project (Donkersgoed et al, 2018). It should be noted, that the number of end-products used as food or feed or of important intermediate products which have been described and coded in the Reports on Objectives 1 and 2 is higher than the number of such products on which the database reports.…”

Section: Database Fieldsmentioning

confidence: 99%

Database of processing techniques and processing factors compatible with the EFSA food classification and description system FoodEx 2 Objective 3: European database of processing factors for pesticides in food

Scholz

Donkersgoed

Herrmann

et al. 2018

EFS3

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EFSA is conducting pan‐European dietary exposure and risk assessments related to actual levels of pesticide residues in food commodities. These assessments use the pesticide occurrence data generated under the official monitoring programs of Member States, the consumption data from EFSA's comprehensive food consumption database and pesticide‐specific information such as processing factors. Currently no harmonised list of processing factors is available within Europe and worldwide. The overall objective of this project is to develop a database of validated processing factors, which is compatible with the EFSA food classification and description system FoodEx 2. In the first part of the project, a compendium of representative processing techniques was elaborated which serves as a standard description of all relevant processes and as a basis for validation of processing studies. In the second part of the project all relevant processes and raw and processed commodities were coded according to FoodEx2. In the third and last part of the project all processing studies used by EFSA in their Conclusions and Reasoned Opinions issued until 30/06/2016 were re‐evaluated according to uniform quality criteria and reported in a database. The database is provided as a flat Excel spreadsheet. Information on processing conditions, on analytical methods, storage stability and GLP was collected from the studies and was used to judge the acceptability of each processing study. The representativeness of the processing conditions applied in the studies was judged by comparing them to the compendium of representative processing techniques. Processing factors (PF) were derived from the studies according to comprehensible calculation rules and based on the residue definitions for monitoring. The individual PF were judged for their acceptability. For each commodity/process/active substance combination a median PF was calculated from the individual ones, based on the trials from one or more studies. The database is a ready‐to‐use inventory of PF for pesticides in a variety of processed food items. In a pilot project a second database was set up with processing factors based on the residue definition for dietary risk assessment. Extension of this database is recommended.

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Section: Database Fieldsmentioning

confidence: 99%

Database of processing techniques and processing factors compatible with the EFSA food classification and description system FoodEx 2 Objective 3: European database of processing factors for pesticides in food

Scholz

Donkersgoed

Herrmann

et al. 2018

EFS3

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“…In a second step of the project, the food/feed items and processes as described in the compendium were coded using the FoodEx2 coding system (Donkersgoed et al, 2018 ), and therefore linked with each other. Additionally, a key facet was added in order to be able to link food and feed items to the EFSA RPC‐model.…”

Section: Appendix F – Information Notes Supporting the Assessment Of ...mentioning

confidence: 99%

Retrospective cumulative dietary risk assessment of craniofacial alterations by residues of pesticides

Anagnostopoulos¹,

Anastassiadou²,

Castoldi³

et al. 2022

EFS2

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EFSA established cumulative assessment groups and conducted retrospective cumulative risk assessments for two types of craniofacial alterations (alterations due to abnormal skeletal development, head soft tissue alterations and brain neural tube defects) for 14 European populations of women in childbearing age. Cumulative acute exposure calculations were performed by probabilistic modelling using monitoring data collected by Member States in 2017, 2018 and 2019. A rigorous uncertainty analysis was performed using expert knowledge elicitation. Considering all sources of uncertainty, their dependencies and differences between populations, it was concluded with varying degrees of certainty that the MOET resulting from cumulative exposure is above 100 for the two types of craniofacial alterations. The threshold for regulatory consideration established by risk managers is therefore not exceeded. Considering the severity of the effects under consideration, it was also assessed whether the MOET is above 500. This was the case with varying levels of certainty for the head soft tissue alterations and brain neural tube defects. However, for the alterations due to abnormal skeletal development, it was found about as likely as not that the MOET is above 500 in most populations. For two populations, it was even found more likely that the MOET is below 500. These results were discussed in the light of the conservatism of the methodological approach.

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“…In a second step of the project, the food/feed items and processes as described in the compendium were coded using the FoodEx2 coding system (van Donkersgoed et al., 2018), and therefore linked with each other. Additionally, a key facet was added in order to be able to link food and feed items to the EFSA RPC‐model.…”

Section: Appendix E – Technical Notes Supporting the Eke Processmentioning

confidence: 99%

Cumulative dietary risk assessment of chronic acetylcholinesterase inhibition by residues of pesticides

Anastassiadou¹,

Choi²,

Čoja³

et al. 2021

EFS2

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A retrospective cumulative risk assessment of dietary exposure to pesticide residues was conducted for chronic inhibition of acetylcholinesterase. The pesticides considered in this assessment were identified and characterised in a previous scientific report on the establishment of cumulative assessment groups of pesticides for their effects on the nervous system. The exposure assessments used monitoring data collected by Member States under their official pesticide monitoring programmes in 2016, 2017 and 2018, and individual food consumption data from 10 populations of consumers from different countries and from different age groups. Exposure estimates were obtained by means of a two-dimensional probabilistic model, which was implemented in SAS ® software. The characterisation of cumulative risk was supported by an uncertainty analysis based on expert knowledge elicitation. For each of the 10 populations, it is concluded with varying degrees of certainty that cumulative exposure to pesticides contributing to the chronic inhibition of acetylcholinesterase does not exceed the threshold for regulatory consideration established by risk managers.

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Cited by 9 publications

References 4 publications

Database of processing techniques and processing factors compatible with the EFSA food classification and description system FoodEx 2 Objective 3: European database of processing factors for pesticides in food

Database of processing techniques and processing factors compatible with the EFSA food classification and description system FoodEx 2 Objective 3: European database of processing factors for pesticides in food

Retrospective cumulative dietary risk assessment of craniofacial alterations by residues of pesticides

Cumulative dietary risk assessment of chronic acetylcholinesterase inhibition by residues of pesticides

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