Death Due To Traumatic Asphyxia in Varanasi Region, India

Khalkho, Satish Kumar; Pathak, Manoj Kumar

doi:10.32598/ijmtfm.v9i2.24129

Cited by 2 publications

(4 citation statements)

References 11 publications

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“…Determining the presence of trauma in forensic medicine is very important in assisting the criminal investigation process. 1 Trauma cannot always be determined through external examination, so an internal examination (autopsy) is needed. 2 Macroscopic examination of organs or body tissues that have been traumatized sometimes does not show satisfactory results.…”

Section: Introductionmentioning

confidence: 99%

“…3 Forensic pathologists are always challenged to prove whether a person died as a result of trauma or not, and the opinion of the forensic pathologists is very important for medico legal purposes. 1,4 In determining the cause of death, including traumatic brain injury (TBI) is usually carried out by internal examination (autopsy), but this is still incomplete because it only leads to the level of epidemiological causes of death not yet leading to causality. 3 Histopathology changes in injuries such as TBI are still being discussed.…”

Section: Introductionmentioning

confidence: 99%

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Comparison between premortem histopathology findings in rats with and without traumatic brain injury: prospective application in forensic medicine

Suryadi,

Kulsum

2024

F1000Res

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Background The aim of this study was to compare pre-mortem histopathology findings in rats with and without traumatic brain injury (TBI) and its prospective application in forensic medicine. Methods This study involved 12 rats with 6 rats for each treatment group. This type of study is a laboratory experimental study with two independent groups design. The first group were rats that did not experience TBI. The second group was a group of rats with TBI. The subjects of this study were Rattus norvegicus rats, adult males, 4-8 weeks old, weighing 150-200 grams. On the 8th day after the rats experienced traumatic brain injury, the rats were then euthanized using the cervical dislocation method, after euthanasia the rats were given craniotomy and brain tissue was taken for histopathology examination. Results The description of histopathology changes in the brain organs in the group of rat without TBI found that neuron cells looked normal although there were also degeneration (21.16 ± 2.56/FV), necrosis (5.75 ± 0.98/FV), apoptosis (2.91 ± 0.80/FV), congestion ( 0.91 ± 0.49/FV), inflammatory cells (4.58 ± 1.15/FV) and hemorrhage (2.41 ± 1.11/FV). Changes in the rat traumatic brain injury group showed a lot of damage to neuron cells in the form of degeneration (48.41 ± 3.27/FV), necrosis (36.66 ± 2.89/FV), apoptosis (18.91 ± 1.24/FV), congestion (2.50 ±0.31/FV), inflammatory cells (11.41 ± 1.71/FV) and hemorrhage (10.08 ± 2.17/FV). Based on the results of statistical analysis, it can be seen that in all parameters there is a significant difference (p ≤ 0.001). Conclusions The premortem histopathology findings in rats with and without TBI which can be used for the benefit of forensic medicine in determining whether TBI is present or not. It is necessary to look more closely at the histopathology changes in the form of necrosis, apoptosis and hemorrhage.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison between premortem histopathology findings in rats with and without traumatic brain injury: prospective application in forensic medicine

Suryadi,

Kulsum

2024

F1000Res

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Comparison between premortem histopathology findings in rats with and without traumatic brain injury: prospective application in forensic medicine

Suryadi,

Kulsum

2023

F1000Res

View full text Add to dashboard Cite

Background: The aim of this study was to compare pre-mortem histopathology findings in rats with and without traumatic brain injury (TBI) and its prospective application in forensic medicine. Methods: This study involved 12 rats with 6 rats for each treatment group. This type of study is a laboratory experimental study with a case control design. The control group were rats that did not experience TBI. The case group was a group of rats with TBI. The subjects of this study were Rattus norvegicus rats, adult males, 4-8 weeks old, weighing 150-200 grams. On the 8th day after the rats experienced traumatic brain injury, the rats were then euthanized using the cervical dislocation method, after euthanasia the rats were given craniotomy and brain tissue was taken for histopathology examination. Results: The description of histopathology changes in the brain organs in the group of rat without TBI found that neuron cells looked normal although there were also degeneration (21.16 ± 2.56/FV), necrosis (5.75 ± 0.98/FV), apoptosis (2.91 ± 0.80/FV), congestion ( 0.91 ± 0.49/FV), inflammatory cells (4.58 ± 1.15/FV) and hemorrhage (2.41 ± 1.11/FV). Changes in the rat traumatic brain injury group showed a lot of damage to neuron cells in the form of degeneration (48.41 ± 3.27/FV), necrosis (36.66 ± 2.89/FV), apoptosis (18.91 ± 1.24/FV), congestion (2.50 ±0.31/FV), inflammatory cells (11.41 ± 1.71/FV) and hemorrhage (10.08 ± 2.17/FV). Based on the results of statistical analysis, it can be seen that in all parameters there is a significant difference (p ≤ 0.001). Conclusions: The premortem histopathology findings in rats with and without TBI which can be used for the benefit of forensic medicine in determining whether TBI is present or not. It is necessary to look more closely at the histopathology changes in the form of necrosis, apoptosis and hemorrhage.

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Death Due To Traumatic Asphyxia in Varanasi Region, India

Cited by 2 publications

References 11 publications

Comparison between premortem histopathology findings in rats with and without traumatic brain injury: prospective application in forensic medicine

Comparison between premortem histopathology findings in rats with and without traumatic brain injury: prospective application in forensic medicine

Comparison between premortem histopathology findings in rats with and without traumatic brain injury: prospective application in forensic medicine

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