Death moment estimation in stillbirth

Knieling, Anton; David, Sofia; Damian, Irina Simona; Iliescu, Diana Bulgaru; Iov, Catalin

doi:10.4323/rjlm.2017.251

Cited by 5 publications

(11 citation statements)

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“…The applicable properties for DFSA, manifested by benzodiazepines intake, are sleepiness, fatigue, dizziness, impaired coordination and/or thinking, memory loss, drowsiness and confusion [14][15][16][17][18]. Benzodiazepines are compounds with lipophilic properties, therefore they are less soluble in polar solvents, as in ethanol and water.…”

Section: Resultsmentioning

confidence: 99%

“…Delayed reporting of sexual assaults by the victims, with the worthlessness of collecting blood and/or urine samples for toxicological examination, the lack of accurate data on the substances used by the offender, as well as the uncertainty of the substance use included in the hospital registry, forces us to analyze the action possibility of other sedative-hypnotic drugs with intravenous intake [16][17][18][19][20][21].…”

Section: Resultsmentioning

confidence: 99%

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Pro-active Drug Facilitated Sexual Assault Using Sedative - hypnotic Medication

Fulga¹,

Neagu²,

Ciubară³

et al. 2019

Rev. Chim.

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Drug facilitated sexual assault (DFSA) can be defined as sexual activity occurring where consent is invalid or absent due to the effects of drugs and/or alcohol. We report a rare case of pro-active drug facilitated sexual assault involving non-oral administration of sedative-hypnotic intoxicant without primary alcoholic ingestion. For eight years, a male nurse administered sedative-hypnotic drugs to patients admitted to the hospital unit, in order to subsequently maintain sexual intercourse with them. The intravenous administration without primary alcoholic ingestion distinguishes this case of pro-active drug facilitated sexual assault from those presented in associated literature.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Pro-active Drug Facilitated Sexual Assault Using Sedative - hypnotic Medication

Fulga¹,

Neagu²,

Ciubară³

et al. 2019

Rev. Chim.

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show abstract

“…The microscopic lesions are highlighted by axonal retraction bulbs. The retraction bulbs are visible at least 4-12 hours after craniocerebral trauma, in arginine impregnation and after one hour by immunohistochemistry techniques, that highlight the presence of the beta-amyloid precursor protein at the level of the affected axons, this becoming the main goal of DAI diagnosis (David et al, 2017;Knieling et al, 2017;Saatman et al, 2003).…”

Section: Introductionmentioning

confidence: 99%

Chemical Biomarkers of Diffusse Axonal Injury

Hunea

Iliescu

Damian

et al. 2020

BRAIN

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Craniocerebral trauma is the most common cause of death and post-traumatic disability in people under 45 years of age. In Romania, the annual incidence shows, that for every 100,000 inhabitants, there are 300 cases of craniocerebral trauma that require specialized medical assistance. Craniocerebral traumas are the most common types of traumas encountered in current forensic practice. Research on the mechanisms of injury, the timing of head trauma and the establishment of causes of death remain relevant. Establishing the traumatic moment implies both the distinction between pre-mortem and post-mortem injuries but also considerations regarding the post-traumatic survival interval. Regarding the elucidation of the moment of occurrence of the craniocerebral trauma from the forensic point of view, a satisfactory result has not been reached so far. The classic hypothesis regarding the development of traumatic brain injuries shows that they are the result of primary traumatic injuries due to cell necrosis combined with the inflammatory brain response that causes secondary brain injuries. It was considered that post-traumatic neuronal losses are strictly due to necrosis and inflammation, and cellular apoptosis being a physiological process, does not play a role in this process. Due to recent experimental data, brain cell apoptosis has begun to be reevaluated. The pathophysiology of traumatic brain injury is far from being fully understood, with the idea that apoptosis would play an even more important role than originally thought. Specifically, damaged brain cells release neuromodulatory substances that can lead to late-onset neuronal damage long after necrotic and inflammatory brain phenomena have ceased to act. These neuronal cell losses are responsible for the development of various neurological deficits and post-traumatic sequelae.

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“…Toxic agents can enter the body in various ways, digestive, respiratory (gases and volatile substances), skin and through conjunctival and nasal mucosa (solvents, pesticides, caustic substances, various ointments, drugs, parenteral (intramuscular, intravenous, subcutaneous) [2][3][4].…”

mentioning

confidence: 99%

Domestic Poisoning in the Pediatric Age Group

2020

Rev.Chim.

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Poisoning in children is a public health issue worldwide, being a 'family disease', an avoidable pathology. Thus, it is the major responsibility of the family to prevent them. Young children, due to their natural curiosity, present a major risk of domestic poisoning. In the case of domestic poisoning in children about half occur in children under 6 years of age, most of them occur in the age range 1 - 4 years. Morbidity and mortality have a higher incidence in childhood. Most of the times domestic poisoning in the case of children is accidental, representing about 85%, but there are also cases of voluntary poisoning. The forensic medicine network has the task of identifying such cases, carrying out forensic expertise and forensic necropsies in the case of deaths, reporting monthly / yearly indicators on the number of deaths per year at the county / national level as well as a series of variables (age and sex groups, environment of origin, cause of poisoning and class of chemical substance), which allow dynamic analysis of time and area tendencies of various population groups, including vulnerable groups. Monitoring such cases allows the establishment of an alert system with the possibility of immediate intervention by the authorities. Within risk assessments, the number of cases of poisoning with a particular substance or class of substances is a fundamental basis for decision making and risk management. Keywords: domestic poisoning, pediatric poisoning

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Death moment estimation in stillbirth

Cited by 5 publications

References 0 publications

Pro-active Drug Facilitated Sexual Assault Using Sedative - hypnotic Medication

Pro-active Drug Facilitated Sexual Assault Using Sedative - hypnotic Medication

Chemical Biomarkers of Diffusse Axonal Injury

Domestic Poisoning in the Pediatric Age Group

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