Decline in mortality in patients with dementia: <scp>R</scp>esults from a nationwide cohort of 44 258 patients in the <scp>N</scp>etherlands during 2000 to 2008

Vorst, Irene E. van de; Vaartjes, Ilonca; Bots, Michiel L.; Koek, Huiberdina L.

doi:10.1002/gps.4960

Cited by 5 publications

(2 citation statements)

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“…Analyses were adjusted for age and stratified by sex. To examine whether level of functioning and morbidity changed over time (2001)(2002)(2003)(2004)(2005)(2006)(2007)(2008)(2009)(2010)(2011)(2012)(2013)(2014)(2015)(2016)(2017)(2018), a linear trend was tested using the contrast command.…”

Section: Discussionmentioning

confidence: 99%

Trends of Physical Functioning, Morbidity, and Disability-Free Life Expectancy Among the Oldest Old: Six Repeated Cross-Sectional Surveys Between 2001 and 2018 in the Vitality 90+ Study

Enroth

Raitanen

Halonen

et al. 2020

The Journals of Gerontology: Series A

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Background It remains unclear whether increasing longevity is accompanied by a compression or expansion of poor health and disability. We examined trends of physical functioning and morbidity in a population aged 90 and older, and disease- and disability-free life expectancy (LE) at age 90 between 2001 and 2018 in Finland’s third most populated city. Methods We used survey data from the Vitality 90+ Study, which comprises a series of six repeated mailed surveys (7,590 observations). Information on mortality came from Statistics Finland. We examined trends of functioning (activities of daily living [ADL] and mobility) and cardiovascular and dementia morbidity using age-adjusted generalized estimating equation models stratified by sex. In addition, age-, sex-, and period-specific health expectancies were calculated using Sullivan’s method. Results Over time, functioning improved, especially, in women, and morbidity increased in men. From 2001 to 2018, LE at age 90 increased by 5.3 months for men and 6.4 months for women. LE without ADL disability increased by 5.0 months for men and 8.4 months for women, and LE without mobility disability by 6.0 months for men and 4.4 months for women. LE without cardiovascular and dementia morbidity decreased for men (2.6 months) and increased for women (1.9 months). Conclusions In relative terms, we found a compression of disability for both sexes and an expansion of morbidity for men. Although the trends overall are rather positive, the increase in absolute morbidity and, to some extent, in disability will inevitably mean increasing care needs with population aging.

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Section: Discussionmentioning

confidence: 99%

Trends of Physical Functioning, Morbidity, and Disability-Free Life Expectancy Among the Oldest Old: Six Repeated Cross-Sectional Surveys Between 2001 and 2018 in the Vitality 90+ Study

Enroth

Raitanen

Halonen

et al. 2020

The Journals of Gerontology: Series A

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“…There is empirical evidence that interprofessional specific programs for PwD in a day clinic lead to a clear improvement in behavioral symptoms and positively influence the distress of caring relatives ( Johansson and Gustafson, 1996 ; Hoe et al, 2005 ; Weber et al, 2009 ; Wunner et al, 2020 ). Furthermore, day clinic treatment of PwD was found to reduce the 1-year hospital readmission risk, as compared to an increased risk among inpatients ( Steinkamp and Werner, 1998 ; van de Vorst et al, 2018 ). In a previous study by our work group, we compared sociodemographic and clinical characteristics of voluntarily treated PwD and their ICs between an inpatient setting and a day clinic setting ( Linnemann et al, 2018 ).…”

Section: Introductionmentioning

confidence: 99%

Psychobiological Evaluation of Day Clinic Treatment for People Living With Dementia – Feasibility and Pilot Analyses

Wuttke-Linnemann¹,

Palm²,

Geschke

et al. 2022

Front. Aging Neurosci.

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BackgroundHospitalization is often stressful and burdensome for people living with dementia (PwD) and their informal caregivers (ICs). Day clinic treatment may provide a suitable alternative, but is often precluded by a diagnosis of dementia. Furthermore, it is often caregiver-based ratings that measure treatment success as the validity of self-reports in PwD is critically discussed. We therefore set out to examine the feasibility of psychobiological stress measures in PwD and ICs and to evaluate treatment trajectories considering both the day clinic context and the daily life of the dyads.MethodA total of 40 dyads of PwD (mean age: 78.15 ± 6.80) and their ICs (mean age: 63.85 ± 13.09) completed paper-and-pencil questionnaires (covering stress, depressive symptoms, and caregiver burden among others) in addition to the measurement of hair cortisol concentrations (HCC) at admission, discharge, and follow-up 6 months after day clinic treatment. As part of an ambulatory assessment, for 2 days at the beginning and 2 days at the end of the day clinic treatment, PwD and ICs collected six saliva samples per day for the analysis of salivary cortisol (sCort) and alpha-amylase (sAA).ResultsPaper-and-pencil questionnaires and HCC assessments were more feasible than the ambulatory assessment. We found discrepancies between subjective and physiological markers of stress in PwD. Whereas HCC decreased over time, self-reported stress increased. Child–parent dyads reported decreases in neuropsychiatric symptoms, associated burden, and self-reported stress from admission to follow-up. In daily life, both PwD and ICs showed characteristic diurnal profiles of sAA and sCort, however, we found no differences in summary indicators of salivary stress markers over time.DiscussionThe psychobiological evaluation was feasible and added informative value, underlining the potential of physiological stress markers to complement self-reports on stress in PwD and to objectively evaluate treatment trajectories. In this sample, HCC was more feasible and acceptable as biological marker of stress compared to saliva samples. Concerning treatment trajectories, differential effects on the dyads were found, with child–parent dyads benefiting more from day clinic treatment compared to spousal dyads.

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Two-decade changes in dementia mortality in a Chinese community

Ding,

Wu,

Xiao

et al. 2024

Aging and Health Research

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Decline in mortality in patients with dementia: Results from a nationwide cohort of 44 258 patients in the Netherlands during 2000 to 2008

Cited by 5 publications

References 28 publications

Trends of Physical Functioning, Morbidity, and Disability-Free Life Expectancy Among the Oldest Old: Six Repeated Cross-Sectional Surveys Between 2001 and 2018 in the Vitality 90+ Study

Trends of Physical Functioning, Morbidity, and Disability-Free Life Expectancy Among the Oldest Old: Six Repeated Cross-Sectional Surveys Between 2001 and 2018 in the Vitality 90+ Study

Psychobiological Evaluation of Day Clinic Treatment for People Living With Dementia – Feasibility and Pilot Analyses

Two-decade changes in dementia mortality in a Chinese community

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