Declining Genetic Polymorphisms of the C-terminus Merozoite Surface Protein-1 Amidst IncreasedPlasmodium knowlesiTransmission in Thailand
Parsakorn Tapaopong,
Sittinont Chainarin,
Abdulrohman Mala
et al.
Abstract:Recent reports from Thailand reveal a substantial surge inPlasmodium knowlesicases over the past decade, with a more than eightfold increase in incidence by 2023 compared to 2018. This study investigates temporal changes in genetic polymorphism associated with the escalating transmission ofP. knowlesimalaria in Thailand over the past two decades. Twenty-fiveP. knowlesisamples collected in 2018–2023 were sequenced for the 42-kDa region ofpkmsp1and compared with 24 samples collected in 2000–2009, focusing on nuc… Show more
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